چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| 2018AbstractIntroduction. – Considering the low level of vitamin B12in diabetic patients on Metformin and also the importance of this vitamin in lipidmetabolism, the aim of the present study was assessing the possible relationship between vitamin B12deficiency, lipid profile and atherogenicindices in Iranian diabetic patients.Method. – In the present cross-sectional study, a sample of 200 patients with type 2 diabetes was selected. Serum level of lipid profile was measuredusing enzymatic colorimetric method. LDL-C was calculated by Friedewald equation and atherogenic indices including total cholesterol to HDL-Cand Log Triglyceride to HDL-C ratio were calculated. Serum level of vitamin B12was measured photometrically using commercial kit.Results. – The prevalence of vitamin B12deficiency was about 14%. There was a significant difference between normal participants and vitaminB12deficient subjects in the case of total cholesterol (P = 0.04). The results of the regression analysis showed that in adjusted model, there wassignificant association between total cholesterol and vitamin B12deficiency (OR: 16.46 [95% CI: 0.27, 33.19], P = 0.04).Conclusion. – The results of the present study showed the relatively high prevalence of the vitamin B12deficiency in type 2 diabetic patients whowere on Metformin. Moreover, there was a significant association between vitamin B12 deficiency and total cholesterol level in diabetic patients.Further studies with larger sample size and considering dietary information and duration of Metformin consumption are needed to confirm thesepreliminary results. |
| نویسنده | نفر چندم مقاله |
|---|---|
| میترا نیافر | اول |
| گلناز صمدی | دوم |
| ناصر آقا محمد زاده | سوم |
| فرزاد نجفی پور | چهارم |
| زینب نیک نیاز | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| vitamin B12.pdf | 1397/03/28 | 564273 | دانلود |
