The effects of ultrasound-guided corticosteroid injection comparedto oxygen–ozone (O2–O3) injection in patients with knee osteoarthritis:a randomized controlled trial

The effects of ultrasound-guided corticosteroid injection comparedto oxygen–ozone (O2–O3) injection in patients with knee osteoarthritis:a randomized controlled trial


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نویسندگان: بینا افتخارسادات

کلمات کلیدی: Corticosteroid.Knee.Osteoarthritis.Oxygen–ozone.Sonography

نشریه: 55104 , in press , in press , 2018

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نویسنده ثبت کننده مقاله بینا افتخارسادات
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه طب فیزیکی وتوانبخشی
کد مقاله 63017
عنوان فارسی مقاله The effects of ultrasound-guided corticosteroid injection comparedto oxygen–ozone (O2–O3) injection in patients with knee osteoarthritis:a randomized controlled trial
عنوان لاتین مقاله The effects of ultrasound-guided corticosteroid injection comparedto oxygen–ozone (O2–O3) injection in patients with knee osteoarthritis:a randomized controlled trial
ناشر 8
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Osteoarthritis (OA) is a chronic multifactorial disease characterized by progressive joint degeneration. The purpose of this studywas to compare the effects of ultrasound-guided corticosteroid injection with oxygen–ozone injection in patients with knee OA.This double-blind randomized clinical trial was performed on 62 patients with knee OA. The patients were randomly divided intotwo groups. In the first group 40 mg triamcinolone (1 cc) and in the second group 10 cc (15 μg/ml) oxygen–ozone (O2–O3) wereinjected into the knee joint under ultrasound guidance. Outcome measures include d the Western Ontario and M cMasterUniversities Osteoarthritis (WOMAC), knee flexion range of motion (ROM), effusion in ultrasound images of the suprapatellarrecess, and visual analog scale (VAS), which were evaluated before injection, 1 week, 1 month, and 3 months after the treatment.Sixty-two patients (10 men and 52 women) were enrolled with mean age of 57.9 years. VAS improved in both groups (steroid Pvalue = 0.001, oxygen–ozone P value > 0.001). The improvements seen in VAS and WOMAC scores 3 months after treatmentwere in favor of the oxygen–ozone group when compared to the steroid group (P = 0.041 vs P = 0.19). There was no significantdifference between the two groups in ROM and joint effusion seen under ultrasound (ROM p = 0.880, effusion p = 0.362).However, in the oxygen–ozone-receiving group, joint effusion was decreased significantly (p < 0.001). Both steroid and oxygen–ozone injections are effective in patients with knee osteoarthritis. Our study showed that the effects of oxygen–ozone injectionlast longer than those of steroid injection to the knee joint.

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بینا افتخارساداتهشتم

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