Identifying Factors Associated with Functional Limitation Among Diabetic Patients in Northwest of Iran: Application of the Generalized Additive Model
Identifying Factors Associated with Functional Limitation Among Diabetic Patients in Northwest of Iran: Application of the Generalized Additive Model
نویسندگان: پروین سربخش , لیلی فرجی گاوگانی , محمد اصغری جعفرآبادی , سید مرتضی شمشیرگران , لیلا جهانگیری
کلمات کلیدی: Diabetes, GAM, Nonlinear Relationship, Functional Limitation
نشریه: 15841 , 2 , 16 , 2018
| نویسنده ثبت کننده مقاله |
پروین سربخش |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز مدیریت و پیشگیری از مصدومیتهای حوادث ترافیکی |
| کد مقاله |
62878 |
| عنوان فارسی مقاله |
Identifying Factors Associated with Functional Limitation Among Diabetic Patients in Northwest of Iran: Application of the Generalized Additive Model |
| عنوان لاتین مقاله |
Identifying Factors Associated with Functional Limitation Among Diabetic Patients in Northwest of Iran: Application of the Generalized Additive Model |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Background: Functional limitation is one of the most important health - related concerns of diabetic patients. This study aimed to
identify the factors associated with functional limitation among diabetic patients using generalized additive model (GAM) as a flexible technique to reveal the non - linear and non - monotonic association between the response and a set of independent variables.
Methods: The source data belonged to two cross - sectional studies conducted in 2014. A total of 694 people with type 2 diabetes
in the age range of 31 - 70 years were selected via convenience sampling from diabetes clinics in Ardabil and Tabriz. The data were
collected by interviewers using structured questionnaires and checklists. The functional capacity was measured using the physical
functioning subscale of the Medical Outcomes Study Short Form 36 - Item Health Survey (SF36). Participants with a total functional
capacity of less than 90 were considered to have “moderate or high level of functional limitation.” To identify the factors associated
with functional limitation and reveal the shape of associations, the GAM procedure with “logit” link function was applied to the
dataset of 378 diabetic patientswithout anymissing data by smoothening of the effect of underlyingfactors. The Akaike information
criterion (AIC) as the relative quality of the model’s criterion was computed for GAM and compared with AIC of the simple logistic
regression.
Results: Sex (P = 0.029), age (P < 0.001), BMI (P = 0.029), and SBP (P = 0.04) were significant in the GAM. Moreover, age with a linear
function (df = 0.98), BMI with quadratic function (df = 1.75), and SBP with the degree 1.33 were significantly related to functional
capacity. AIC of the GAM was lower than that of the logistic model.
Conclusions: In our sample, GAM could identify some linear and nonlinear associations between underlying factors and functional
limitation in diabetic patients. These complex associations could relatively increase the fit quality of the GAM when compared to
logistic regression. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| GAM.pdf | 1397/02/16 | 283053 | دانلود |