Identifying Factors Associated with Functional Limitation Among Diabetic Patients in Northwest of Iran: Application of the Generalized Additive Model

Identifying Factors Associated with Functional Limitation Among Diabetic Patients in Northwest of Iran: Application of the Generalized Additive Model


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نویسندگان: پروین سربخش , لیلی فرجی گاوگانی , محمد اصغری جعفرآبادی , سید مرتضی شمشیرگران , لیلا جهانگیری

کلمات کلیدی: Diabetes, GAM, Nonlinear Relationship, Functional Limitation

نشریه: 15841 , 2 , 16 , 2018

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نویسنده ثبت کننده مقاله پروین سربخش
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز مدیریت و پیشگیری از مصدومیتهای حوادث ترافیکی
کد مقاله 62878
عنوان فارسی مقاله Identifying Factors Associated with Functional Limitation Among Diabetic Patients in Northwest of Iran: Application of the Generalized Additive Model
عنوان لاتین مقاله Identifying Factors Associated with Functional Limitation Among Diabetic Patients in Northwest of Iran: Application of the Generalized Additive Model
ناشر 5
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background: Functional limitation is one of the most important health - related concerns of diabetic patients. This study aimed to identify the factors associated with functional limitation among diabetic patients using generalized additive model (GAM) as a flexible technique to reveal the non - linear and non - monotonic association between the response and a set of independent variables. Methods: The source data belonged to two cross - sectional studies conducted in 2014. A total of 694 people with type 2 diabetes in the age range of 31 - 70 years were selected via convenience sampling from diabetes clinics in Ardabil and Tabriz. The data were collected by interviewers using structured questionnaires and checklists. The functional capacity was measured using the physical functioning subscale of the Medical Outcomes Study Short Form 36 - Item Health Survey (SF36). Participants with a total functional capacity of less than 90 were considered to have “moderate or high level of functional limitation.” To identify the factors associated with functional limitation and reveal the shape of associations, the GAM procedure with “logit” link function was applied to the dataset of 378 diabetic patientswithout anymissing data by smoothening of the effect of underlyingfactors. The Akaike information criterion (AIC) as the relative quality of the model’s criterion was computed for GAM and compared with AIC of the simple logistic regression. Results: Sex (P = 0.029), age (P < 0.001), BMI (P = 0.029), and SBP (P = 0.04) were significant in the GAM. Moreover, age with a linear function (df = 0.98), BMI with quadratic function (df = 1.75), and SBP with the degree 1.33 were significantly related to functional capacity. AIC of the GAM was lower than that of the logistic model. Conclusions: In our sample, GAM could identify some linear and nonlinear associations between underlying factors and functional limitation in diabetic patients. These complex associations could relatively increase the fit quality of the GAM when compared to logistic regression.

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نویسنده نفر چندم مقاله
پروین سربخشدوم
لیلی فرجی گاوگانیاول
محمد اصغری جعفرآبادیسوم
سید مرتضی شمشیرگرانچهارم
لیلا جهانگیریپنجم

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GAM.pdf1397/02/16283053دانلود