Frequency of Smear-Negative Tuberculosis in Northwest Iran

Frequency of Smear-Negative Tuberculosis in Northwest Iran


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نویسندگان: محیا پوراستادی , جلیل راشدی , بهروز مهدوی پور صباحی , حسین صمدی کفیل , محمد اصغرزاده

کلمات کلیدی: Culture ● Diagnosis ● Epidemiology ● Smear ● Tuberculosis

نشریه: 55266 , 3 , 43 , 2018

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نویسنده ثبت کننده مقاله جلیل راشدی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده پیراپزشکی
کد مقاله 62876
عنوان فارسی مقاله Frequency of Smear-Negative Tuberculosis in Northwest Iran
عنوان لاتین مقاله Frequency of Smear-Negative Tuberculosis in Northwest Iran
ناشر 6
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background: Microscopic smear examination is the most common test in tuberculosis (TB) detection. It is, however, not strong enough to identify TB in the majority of afflicted individuals; thus, a significant number of TB patients are smear negative and capable of transmitting the infection. The aim of this study was to evaluate the rate of smear-negative TB in northwest Iran. Methods: In this cross-sectional study, 329 TB-confirmed patients were evaluated through culture up to March 1, 2015, in northwest Iran. The demographic and clinical features of the smear-negative and smear-positive TB patients were compared. The χ2 test was used to compare the frequency of the variables. All the statistical analyses were conducted using SPSS, version 16 (Chicago, IL, USA). Results: Seventy-five cases were smear negative and 254 were smear positive. Smokers, asthmatics, and extra-pulmonary TB patients were primarily among the smear-negative cases. The rate of mortality was also relatively higher among the smearnegative TB patients. Conclusion: Totally, 22.8% of the TB cases in northwest Iran were smear negative, with a relatively higher rate of mortality than those with positive smears. A delay in these patients’ return to TB diagnosis and treatment centers increases the chance of transmission to others. This is a very sensitive issue in centers where there is no equipment for TB cultivation. Thus, it is essential to equip centers without TB cultivation facilities and to use appropriate diagnostic techniques in centers with those facilities to help rapidly detect smear-negative cases.

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نویسنده نفر چندم مقاله
محیا پوراستادیاول
جلیل راشدیدوم
بهروز مهدوی پور صباحیسوم
حسین صمدی کفیلچهارم
محمد اصغرزادهششم

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Smear negative .pdf1397/02/16258133دانلود