چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| 2018AbstractAim. – Metabolic syndrome (MetS) is a clinical disorder with widespread prevalence. In the current study, we aimed to investigate the serumvalues of macrophage inhibitory cytokine (MIC)-1, vascular endothelial growth factor (VEGF) and markers of oxidative stress among patientswith metabolic syndrome.Material and methods. – Twenty obese patients with MetS and 20 obese apparently healthy controls were participated in the current case-controlstudy. The participants’ body mass index (BMI), waist circumference (WC), systolic and diastolic blood pressure (SBP and DBP) were measured.Serum levels of total cholesterol (TC), triglyceride (TG), low and high density lipoprotein cholesterol (LDL-c and HDL-c), vascular endothelialgrowth factor (VEGF), MIC-1 (macrophage inhibitory cytokine 1), superoxide dismutase (SOD) and glutathione peroxidase (GPX) were alsodetermined by commercial ELIZA kits.Results. – Participants in MetS group had higher levels of WC, DBP and higher serum concentrations of TG and TC compared with control group(P < 0.05). Serum VEGF and MIC-1 levels were significantly higher in patients with MetS compared with control subjects (P < 0.05). There wasa significant and positive association between serum levels of VEGF and LDL (P = 0.027; = 0.453) in all of the study participants. Moreover, aninverse association between serum GPX with DBP and between SOD with WC were also seen (P < 0.05).Conclusion. – The higher serum values of MIC-1 and VEGF in patients with MetS and the negative association of VEGF with serum LDLconcentrations opened a new window about the possible pathologic role of these factors in the etiology or pathophysiology of MetS. Further studiesare warranted for solidification of achieved results. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهدیه عباسعلیزاد فرهنگی | دوم |
| عاطفه شریعت | اول |
| ریحانه زینلیان | سوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Spirulina Descriptive 2.pdf | 1397/02/06 | 772372 | دانلود |
| Tahodnameh.doc | 1397/02/06 | 47616 | دانلود |
