Myeloid-derived suppressor cells: Important contributors to tumor progression and metastasis
Myeloid-derived suppressor cells: Important contributors to tumor progression and metastasis
نویسندگان: الهام صفرزاده , حامد محمدی , فرهاد بابایی , بهزاد برادران
کلمات کلیدی: angiogenesis, cancer, metastasis, myeloid-derived suppressor cells (MDSCs), tumor
microenvironment
نشریه: 19614 , 4 , 233 , 2017
| نویسنده ثبت کننده مقاله |
بهزاد برادران |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات ایمونولوژی |
| کد مقاله |
62349 |
| عنوان فارسی مقاله |
Myeloid-derived suppressor cells: Important contributors to tumor progression and metastasis |
| عنوان لاتین مقاله |
Myeloid-derived suppressor cells: Important contributors to tumor progression and metastasis |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
http://onlinelibrary.wiley.com/doi/10.1002/jcp.26075/full |
| Myeloid-derived suppressor cells (MDSCs) are traditionally considered among the
major components of the immunosuppressive tumor microenvironment (TME).
However, there is currently increasing evidence indicating that MDSCs in addition
to suppression of immune surveillance is also involved in an array of nonimmunological functions like augmenting metastatic potential of tumor cells. Indeed,
MDSCs can promote metastasis in animal models and cancer patients through
promoting premetastatic nicheformation, tumorangiogenesisand invasion.Moreover,
MDSC frequency and function have been associated with progressive disease and
correlated with clinical outcome. This review will summarize and discusses the data
demonstrating the role for MDSCs in tumor metastasis |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 190-Myeloid-derived suppressor cells Important contributors totumor progression and metastasis.pdf | 1396/11/26 | 701325 | دانلود |