Is treatment of fatty liver effective on reducing carotid intima media thickness: A cohort study

Is treatment of fatty liver effective on reducing carotid intima media thickness: A cohort study


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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: سعیده غفاری فر , منوچهر خوشباطن , مریم زارع نهندی , رضا جواد رشید

کلمات کلیدی: Carotid, Intima Media thickness; Color Doppler Sonography, Fatty Liver

نشریه: 12452 , 1 , 11 , 2018

اطلاعات کلی مقاله
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نویسنده ثبت کننده مقاله سعیده غفاری فر
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات آموزش علوم پزشکی
کد مقاله 62328
عنوان فارسی مقاله Is treatment of fatty liver effective on reducing carotid intima media thickness: A cohort study
عنوان لاتین مقاله Is treatment of fatty liver effective on reducing carotid intima media thickness: A cohort study
ناشر 6
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح دو – PubMed
آدرس لینک مقاله/ همایش در شبکه اینترنت http://journals.sbmu.ac.ir/ghfbb/index.php/ghfbb/article/view/1112/748

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Aim: This study was intended to explore the effect of various drugs used to treat fatty liver on intimal-media thickness in patients with NAFLD. Background: Nonalcoholic fatty liver disease (NAFLD) is an indicator of a broad spectrum of pathologic disorders, which is characterized with macro vesicular steatosis in the absent of alcohol use. It has a wide range of laboratory, clinical and pathological presentations such as simple steatosis to the diseases like non-alcoholic steatohepatitis, fibrosis, and cirrhosis and hepatocellular cancer. Methods: In this cross - sectional study, as a part of a 10-year cohort study (from 2007-2017) at Tabriz University of Medical Sciences, a group of 100 patients with NAFLD were studied. They were examined by color doppler sonography of the carotid arteries to detect any carotid intima- media thickness, before and one year after treatment with various drugs. The effect of treatment on right and left carotid intima- media thickness (IMT) was examined by using SPSS. V21. Results: Over all, 36 (36%) patients were male and 64 (64%) were female. The mean age of the patients was a 43.5±10.3 year, ranging from 16 to 64. The decrease in patients' intima- media thickness in both right and left carotids was statistically significant (P<0.0001). Conclusion: Treatment of patients with nonalcoholic fatty liver has a significant role in reduction of their carotid intima -media thickness and consequently in reducing cerebrovascular events such as stroke.

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نویسنده نفر چندم مقاله
سعیده غفاری فراول
منوچهر خوشباطندوم
مریم زارع نهندیچهارم
رضا جواد رشیدپنجم

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نام فایل تاریخ درج فایل اندازه فایل دانلود
2018 PubMed article Ghaffarifar.pdf1396/12/11260505دانلود