The effect mucoadhesive gel containing Satureja hortensis extract of 1% on severity of chemotherapy-induced mucositis pain in children: A randomized double-blind clinical trial

The effect mucoadhesive gel containing Satureja hortensis extract of 1% on severity of chemotherapy-induced mucositis pain in children: A randomized double-blind clinical trial


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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: محمد ارشدی بستان آباد , امیر عطااله هیرادفر , اصغر محمدپوراصل , یوسف جوادزاده , باقر خلوتی , طاهره الوندنژاد مجارنشین

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نشریه: 0 , 5 , 6 , 2018

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نویسنده ثبت کننده مقاله محمد ارشدی بستان آباد
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده پرستاری و مامائی
کد مقاله 62231
عنوان فارسی مقاله The effect mucoadhesive gel containing Satureja hortensis extract of 1% on severity of chemotherapy-induced mucositis pain in children: A randomized double-blind clinical trial
عنوان لاتین مقاله The effect mucoadhesive gel containing Satureja hortensis extract of 1% on severity of chemotherapy-induced mucositis pain in children: A randomized double-blind clinical trial
ناشر 6
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق) International Journal of Pediatrics
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت http://ijp.mums.ac.ir/volume_1327.html

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Background: One of the symptoms of mucositis caused by chemotherapy is pain. Mucositis management is initiated by assessment of oral hygiene and management of pain. Many uses have been mentioned for Satureja hortensis in traditional medicine. The study was carried out with the aim of determining the effect of Satureja hortensis extract mucoadhesive gel of 1% on severity of mucositisinduced pain in children under chemotherapy. Materials and Methods This randomized parallel double-blind clinical trial was carried out on 60 children who were affected by mucositis following chemotherapy in 2016. The samples were randomly assigned into two groups of intervention and control. The intervention group applied Satureja hortensis extract gel of 1% and the control group applied the placebo gel twice daily for 5 days after the onset of mucositis along with routine treatment. Oral mucosa was evaluated daily. Also, the Oucher pain tools and a demographic checklist were used. The data was analyzed using SPSS version 13.0 software. Results: The obtained data showed that the two groups had statistical difference in terms of the severity of the pain relief during the time, and pain severity reduced from 3.5±2.1 to 0.0 ± 0.0 in intervention group and 3.1 ± 1.8 to 0.4 ± 1.0 in control group in fifth day (p <0.001). Conclusion The study showed that the extract 1% of Satureja hortensis is effective in healing mucositis induced pain and can be used as a new treatment method in relieving reducing mucositis pain. Key Words: Children, Chemotherapy, Mucositis, Pain, Satureja hortensis.

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نویسنده نفر چندم مقاله
محمد ارشدی بستان آباداول
امیر عطااله هیرادفردوم
اصغر محمدپوراصلسوم
یوسف جوادزادهچهارم
باقر خلوتیپنجم
طاهره الوندنژاد مجارنشینششم

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IJP_Volume 6_Issue 5_Pages 7605-7614.pdf1397/01/14336227دانلود