The effect mucoadhesive gel containing Satureja hortensis extract of 1% on severity of chemotherapy-induced mucositis pain in children: A randomized double-blind clinical trial
The effect mucoadhesive gel containing Satureja hortensis extract of 1% on severity of chemotherapy-induced mucositis pain in children: A randomized double-blind clinical trial
نویسندگان: محمد ارشدی بستان آباد , امیر عطااله هیرادفر , اصغر محمدپوراصل , یوسف جوادزاده , باقر خلوتی , طاهره الوندنژاد مجارنشین
کلمات کلیدی:
نشریه: 0 , 5 , 6 , 2018
| نویسنده ثبت کننده مقاله |
محمد ارشدی بستان آباد |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پرستاری و مامائی |
| کد مقاله |
62231 |
| عنوان فارسی مقاله |
The effect mucoadhesive gel containing Satureja hortensis extract of 1% on severity of chemotherapy-induced mucositis pain in children: A randomized double-blind clinical trial |
| عنوان لاتین مقاله |
The effect mucoadhesive gel containing Satureja hortensis extract of 1% on severity of chemotherapy-induced mucositis pain in children: A randomized double-blind clinical trial |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
International Journal of Pediatrics |
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
http://ijp.mums.ac.ir/volume_1327.html |
| Background: One of the symptoms of mucositis caused by chemotherapy is pain. Mucositis
management is initiated by assessment of oral hygiene and management of pain. Many uses have been
mentioned for Satureja hortensis in traditional medicine. The study was carried out with the aim of
determining the effect of Satureja hortensis extract mucoadhesive gel of 1% on severity of mucositisinduced
pain in children under chemotherapy.
Materials and Methods
This randomized parallel double-blind clinical trial was carried out on 60 children who were affected
by mucositis following chemotherapy in 2016. The samples were randomly assigned into two groups
of intervention and control. The intervention group applied Satureja hortensis extract gel of 1% and
the control group applied the placebo gel twice daily for 5 days after the onset of mucositis along with
routine treatment. Oral mucosa was evaluated daily. Also, the Oucher pain tools and a demographic
checklist were used. The data was analyzed using SPSS version 13.0 software.
Results: The obtained data showed that the two groups had statistical difference in terms of the
severity of the pain relief during the time, and pain severity reduced from 3.5±2.1 to 0.0 ± 0.0 in
intervention group and 3.1 ± 1.8 to 0.4 ± 1.0 in control group in fifth day (p <0.001).
Conclusion
The study showed that the extract 1% of Satureja hortensis is effective in healing mucositis induced
pain and can be used as a new treatment method in relieving reducing mucositis pain.
Key Words: Children, Chemotherapy, Mucositis, Pain, Satureja hortensis. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| IJP_Volume 6_Issue 5_Pages 7605-7614.pdf | 1397/01/14 | 336227 | دانلود |