چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | زینب لطیفی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز جامع سلولهای بنیادی و پزشکی بازساختی SCARM |
| کد مقاله | 62205 |
| عنوان فارسی مقاله | Potential roles of metalloproteinases of endometrium-derived exosomes in embryo-maternal crosstalk during implantation |
| عنوان لاتین مقاله | Potential roles of metalloproteinases of endometrium-derived exosomes in embryo-maternal crosstalk during implantation |
| ناشر | 5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Review Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://onlinelibrary.wiley.com/doi/10.1002/jcp.26259/full |
| During embryo implantation, crosstalk between the endometrial epithelium and the blastocyst, especially the trophoblasts, is a prerequisite for successful implantation. During this crosstalk, various molecular and functional changes occur to promote synchrony between the embryo and the endometrium as well as the uterine cavity microenvironment. In the past few years, growing evidence has shown that endometrium-derived exosomesplay pivotal rolesin theembryonic-maternal crosstalk during implantation, although the exact mechanism of this crosstalk has yet to be determined. The presence of metalloproteinases has been reported in endometriumderived exosomes, implying the importance of these enzymes in exosome-based crosstalk. Thus,in thisreview, wedescribe thepotential rolesof themetalloproteinases of endometrium-derived exosomes in promoting embryo attachment and implantation. This study could provide a better understanding of the potential roles of exosomal metalloproteinases in embryo implantation and pave the way for developing novel exosome-based regulatory agents to support early pregnancy. |
| نویسنده | نفر چندم مقاله |
|---|---|
| زینب لطیفی | اول |
| امیر فتاحی | دوم |
| حمیدرضا نجابتی | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 14781911.pdf | 1396/11/02 | 1153607 | دانلود |
