چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | حامد حاجی پور |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده علوم نوین پزشکی |
| کد مقاله | 62007 |
| عنوان فارسی مقاله | اثر ترکیبات غذایی بر تنظیم تغییرات اپی ژنتیکی در سرطان |
| عنوان لاتین مقاله | The Effect of Dietary Constituents on Regulation of Epigenetic Changes in Cancer |
| ناشر | 4 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Review Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح سه – Scopus |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://jbums.org/article-1-6445-en.html |
| BACKGROUND AND OBJECTIVE: The term “epigenetic” refers to all non-heritable and reversible changes in the expression of a gene that does not cause a change in the DNA sequence. The most important epigenetic mechanisms associated with gene expression include DNA methylation, histone modifications, and suppression of gene expression with RNA. Considering the reversibility of epigenetic changes, it seems that this feature can be influenced by dietary constituents and thus, we can prevent the spread of certain cancers by controlling the diet. The purpose of this study is to investigate the effects of food on the prevention of common cancers and the mechanisms involved in cellular activities based on recent studies and the compilation of their results. METHODS: In this review article, we searched Pubmed and Elsevier databases using certain keywords such as “epigenetics”, “cancer” and “nutrition” and articles related to the effects of epigenetics on cancer and dietary constituents were evaluated. FINDINGS: Of 439 studies found in the search engines between 1997 and 2016, 64 articles were selected and their results indicated that many of the active components in the diet will inhibit the incidence of cancer through DNA methylation mechanisms, histone modifications, and miRNA. CONCLUSION: The anticancer effect of the active compounds in the diet on specific epigenetic changes can be used as a special and unidentified mechanism for preventing cancer. |
| نویسنده | نفر چندم مقاله |
|---|---|
| حامد حاجی پور | سوم |
| سیامک برقی | اول |
| مریم امیری | دوم |
| سعید نمکی | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| hamed hajipour.pdf | 1396/10/03 | 406184 | دانلود |
