The Future of Diabetes Management by Healthy Probiotic Microorganisms

The Future of Diabetes Management by Healthy Probiotic Microorganisms


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نویسندگان: عزیز همایونی راد

کلمات کلیدی: Diabetes, gut microbes, intestinal microbiota, probiotics, inflammatory, chronic diseases.

نشریه: 8670 , 6 , 13 , 2017

اطلاعات کلی مقاله
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نویسنده ثبت کننده مقاله عزیز همایونی راد
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده تغذیه
کد مقاله 61990
عنوان فارسی مقاله The Future of Diabetes Management by Healthy Probiotic Microorganisms
عنوان لاتین مقاله The Future of Diabetes Management by Healthy Probiotic Microorganisms
ناشر 11
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Review Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت http://www.eurekaselect.com/146299/article

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Background: Diabetes mellitus, a condition of multifactorial origin, is related to the intestinal microbiota by numerous molecular mechanisms. Controlling the vast increase in the prevalence of diabetes needs a natural and safe solution. Probiotics, known as live microorganisms that exert health benefits to the host, have anti-diabetic property. Objective: This review will highlight the current evidences in probiotic effectiveness and future prospects for exploring probiotic therapy in the prevention and control of diabetes. Methods: We searched Pub Med and Science Direct by using “Probiotics” and “Diabetes” for searching the studies aiming the application of probiotics and the beneficial effects of probiotics in diabetes prevention and control. Results: It has been shown that probiotics can increase insulin sensitivity and reduce autoimmune responses by modulating intestinal microbiota and decreasing the inflammatory reactions and oxidative stress. Recent evidences show that probiotics influences the host through modulating intestinal permeability and mucosal immune response, manipulating eating behaviors by appetite-regulating hormones and controlling gut endocannabinoid (eCB) system that is believed to be associated with inflammation and diabetes. Moreover, modulating the intestinal microbiota by probiotics controls host metabolism by affecting energy extraction from food and by biochemically converting molecules derived from the host or from gut microbes themselves. Conclusion: Experimental and clinical evidences support the hypothesis that the modulation of the gut microbiota by probiotics could be effective in prevention and management of diabetes.

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عزیز همایونی راداول

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The Future of Diabetes Management by Healthy Probiotic Microorganisms.pdf1396/09/301228018دانلود