Comparing the efficacy of desmopressin and oxybutynin combination therapy and desmopressin monotherapy in children with primary nocturnal enuresis; a randomized clinical trial

Comparing the efficacy of desmopressin and oxybutynin combination therapy and desmopressin monotherapy in children with primary nocturnal enuresis; a randomized clinical trial


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نویسندگان: افشین قلعه گلاب بهبهانی , فخرالسادات مرتضوی

کلمات کلیدی: Desmopressin Oxybutynin Primary nocturnal enuresis

نشریه: 0 , 4 , 6 , 2017

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نویسنده ثبت کننده مقاله افشین قلعه گلاب بهبهانی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات سلامت کودکان
کد مقاله 61929
عنوان فارسی مقاله Comparing the efficacy of desmopressin and oxybutynin combination therapy and desmopressin monotherapy in children with primary nocturnal enuresis; a randomized clinical trial
عنوان لاتین مقاله Comparing the efficacy of desmopressin and oxybutynin combination therapy and desmopressin monotherapy in children with primary nocturnal enuresis; a randomized clinical trial
ناشر 9
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق) Journal of Renal Injury Prevention
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح دو – PubMed
آدرس لینک مقاله/ همایش در شبکه اینترنت http://www.journalrip.com/Abstract/JRIP_20170723173303

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Introduction: Nocturnal enuresis is known as the most common developmental problems of childhood which has often a familial basis. It is usually benign and gradually disappears with age. Objectives: This study was conducted on children with primary nocturnal enuresis to compare the efficacy of desmopressin and oxybutynin combination therapy with desmopressin monotherapy. Patients and Methods: This clinical trial was conducted on 59 patients (age range; 5 to 15 years) with primary nocturnal enuresis who had referred to our center in Tabriz in 2012. The participants were divided into two groups as group 1 (30 participants) and group 2 (29 subjects). For three months, one group received desmopressin and oxybutynin and the other group received desmopressin alone. Descriptive statistics (mean ± SD and frequency) and chi-square test was conducted. Results: In the group treated only with desmopressin, 72.4% of the participants were completely cured in 1 month and 44.8% in 3 months. In the group treated with combination of desmopressin and oxybutynin, 83.34% were cured in 1 month and 86.7% in 3 months. Conclusion: Desmopressin and oxybutynin combination therapy is more effective than desmopressin monotherapy for treating children with enuresis.

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نویسنده نفر چندم مقاله
افشین قلعه گلاب بهبهانیسوم
فخرالسادات مرتضویچهارم

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Dr. Behbahan JRIP_20170723173303.pdf1396/09/19382539دانلود