| Biosensors combine the sensitivity of detection technology with the specificity of a designated biological
entity. Owing to their specificity and sensitivity, biosensors are applied for sensing and monitoring of
different diseases. Simultaneous sensing of myriad of biomarkers in different diseases at the early stages
is swiftly finding its way towards disease's hallmarks, even though the biological contexts are complex
matrices with possible cross-reactivity of restrained biomolecules. Electrochemical biosensors are
considered as simple and cost-effective methods, which make the concurrent detection of multiple
biomarkers plausible for ultimate diagnosis of diseases in clinic. Simultaneous sensing of multiple biomarkers
by electrochemical techniques can be achieved through either multi-label or multi-electrode
approaches, which can be implemented as miniaturized screen-printed or even lab-on-a-chip systems.
Here, we reviewed literature (2000e2016) and provided a comprehensive insight on various biosensing
platforms, articulating the most recent advancements in each type of biosensors applied for the detection
of biomolecules |