Ciliary neurotrophic factor (CNTF) delivery to retina: an overview of current research advancements
Ciliary neurotrophic factor (CNTF) delivery to retina: an overview of current research advancements
نویسندگان: نصرت اله ضرغامی , عفت علیزاده , خاطره ساعی ارزومند , بهزاد فلاحی مطلق , مریم قاسمی
کلمات کلیدی: CNTF; delivery; encapsulated cell technology; retina; viral vectors
نشریه: 39930 , 0 , 0 , 2018
| نویسنده ثبت کننده مقاله |
نصرت اله ضرغامی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز سلولهای بنیادی |
| کد مقاله |
61775 |
| عنوان فارسی مقاله |
Ciliary neurotrophic factor (CNTF) delivery to retina: an overview of current research advancements |
| عنوان لاتین مقاله |
Ciliary neurotrophic factor (CNTF) delivery to retina: an overview of current research advancements |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
Artificial Cells, Nanomedicine and Biotechnology |
| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
http://www.tandfonline.com/doi/abs/10.1080/21691401.2017.1391820?journalCode=ianb20 |
| The intraocular administration of the ciliary neurotrophic factor (CNTF) has been found to attenuate the photoreceptor degeneration and preserve retinal functions in the animal research models of the inherited or induced retinal disease. Studies with the aim of CNTF transfer to the posterior segment inside the eye have been directed to determine the best method for its administration. An ideal delivery method would overcome the eye drug elimination mechanisms or barriers and provide the sustained release of the CNTF into retina in the safest fashion with the minimum harm to the quality of life. This review focuses on the present state of CNTF delivery to retina, also provides an overview of available technologies and their challenges. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 10.1080@21691401.2017.1391820.pdf | 1396/11/08 | 1525227 | دانلود |