Predictive factors for achieving independent walking in children with Guillain-Barre syndrome

Predictive factors for achieving independent walking in children with Guillain-Barre syndrome


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نویسندگان: محمد برزگر , وحیده توپچی زاده تبریزیان , محمد حسن کارگر ماهر , فاطمه جهانجو , علیرضا پیش گاهی

کلمات کلیدی: Predictive factors ، children، Guillain-Barre syndrome

نشریه: 55425 , 2 , 82 , 2017

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نویسنده ثبت کننده مقاله وحیده توپچی زاده تبریزیان
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه طب فیزیکی وتوانبخشی
کد مقاله 61728
عنوان فارسی مقاله Predictive factors for achieving independent walking in children with Guillain-Barre syndrome
عنوان لاتین مقاله Predictive factors for achieving independent walking in children with Guillain-Barre syndrome
ناشر 6
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت https://www.nature.com/pr/journal/v82/n2/full/pr201767a.html

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BACKGROUND: To determine the predictors of achieving independent walking at 2 and 6 months after onset of weakness in children with Guillain-Barre syndrome (GBS). METHODS: Children with GBS admitted to the Tabriz Children’s Hospital were studied prospectively. All patients had frequent clinical evaluations until achieving independent walking. Unaided walking at 2 and 6 months and factors influencing these outcomes were determined using both univariate and multiple analyses. RESULTS: Between 2003 and 2014, 324 children (mean age: 5.3 ± 3.66 years) were admitted. The mean duration to independent walking was 2.97 ± 3.02 months; 90.5% of patients could walk independently at 6 months. In the univariate analysis, disability score of 43 (P = 0.03), autonomic nerve involvement (P = 0.003), cranial nerve involvement (P = 0.008), and absent compound muscle action potential (CMAP; P = 0.048) were found to be significantly associated with poor walking outcome at 6 months. In the multivariate analysis, cranial nerve involvement (P = 0.008) and absence of CMAP (P = 0.022) were independently associated with poor functional outcome. CONCLUSION: Disability score 43, cranial and autonomic nerve involvement, and absence of CMAP were predictors of independent walking in childhood GBS in this study; early rehabilitation program may prevent further impairments secondary to immobility in these patients.

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نویسنده نفر چندم مقاله
محمد برزگراول
وحیده توپچی زاده تبریزیاندوم
محمد حسن کارگر ماهرسوم
فاطمه جهانجوپنجم
علیرضا پیش گاهیششم

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