Effects of Analytical Procedures on the Repeatability of Malondialdehyde Determinations in Biological Samples
Effects of Analytical Procedures on the Repeatability of Malondialdehyde Determinations in Biological Samples
نویسندگان: سجاد عزیزی خواجه , مریم خوب نسب جعفری , مهری خوب نسب جعفری , جعفر سلیمانی , ابوالقاسم جویبان
کلمات کلیدی: -Malondialdehyde
-Thiobarbituric acid
-Derivatization
-Reproducibility
-Human plasma
نشریه: 27159 , 3 , 23 , 2017
| نویسنده ثبت کننده مقاله |
مریم خوب نسب جعفری |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات سل و بیماری های ریوی |
| کد مقاله |
61702 |
| عنوان فارسی مقاله |
Effects of Analytical Procedures on the Repeatability of Malondialdehyde Determinations in Biological Samples |
| عنوان لاتین مقاله |
Effects of Analytical Procedures on the Repeatability of Malondialdehyde Determinations in Biological Samples |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
http://journals.tbzmed.ac.ir/PHARM/Abstract/PHARM_15814_20161110154220 |
| Malondialdehyde (MDA) is a commonly used biomarker of
oxidative stress in clinical studies and has been measured in many pathological
conditions during last decades. Different analytical methods have been reported
for determination of MDA in biological samples in which MDA was adducted
with thiobarbituric acid (TBA) to produce more sensitive chromophore and also
convert it to a fluorescent compound. In spite of the routine applications of this
derivatization and subsequent analysis of MDA in biomedical studies, its
reliability, repeatability and reproducibility is questionable. The aim of this
work is to investigate the effects of some factors on the repeatability of MDA
determinations in standard solutions and also in plasma samples using
spectroscopic method. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| pharmaceutical sciences, 2017, 23,193-197.pdf | 1396/08/15 | 588209 | دانلود |