| خلاصه مقاله | Background and Aim: Guillain-barre Syndrome (GBS) has a highly variable course and outcome. The aim of this study was to evaluate long-term and short -term outcome and predictors of poor outcome of GBS among children.
Methods: Children with GBS admitted over 11 years in Tabriz children Hospital were studies prospectively . All patients had frequent clinical evaluations during hospital admission and after being discharged unit achieving independent walking.
Results: Between 2003 and 2014, 324 children (mean age 5.3+- 3.66 years ) were admitted. Thirty one (9.6%) patients required artificial ventilation and five (1.5%) patients expired. Mean duration for independent walking was 2.97+-3.02 months, 96% of the sufferers were
occurred in 1.8% of the patients. Cranial nerve involvemen, autonomic dysfunction, axonal pattern and absent compound muscle action potential ( OR :6.47, P:0.001) were associated with short-term poor outcome. In addition, Young age, cranial nerve involvement,
autonomic able to walk unit one year. Relapse dysfunction, high grade disability (OR :20.65, P:0.001) , axonal pattern and absent compound muscle action potential (OR:18, P:0.001) were poor predictors of acheiving independent walking
Conclusion: Although 9.6% were finally mechanically ventilated and mortality was 1.5%, 9.6%were able to walk independently unit one year. clinival and electrophysiologic finding may predict poor outcome in children GBS. |