Essential Oil from Flowers and Leaves of Elaeagnus Angustifolia (Elaeagnaceae): Composition, Radical Scavenging and General Toxicity Activities

Essential Oil from Flowers and Leaves of Elaeagnus Angustifolia (Elaeagnaceae): Composition, Radical Scavenging and General Toxicity Activities


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نویسندگان: محمدعلی تربتی , سولماز اثناعشری , فریبا حشمتی افشار

کلمات کلیدی: Elaeagnus angustifolia L., Essential oil , Radical scavenging activity, General toxicity, E-ethyl cinnamate

نشریه: 952 , 2 , 6 , 2017

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نویسنده ثبت کننده مقاله فریبا حشمتی افشار
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده داروسازی
کد مقاله 61617
عنوان فارسی مقاله Essential Oil from Flowers and Leaves of Elaeagnus Angustifolia (Elaeagnaceae): Composition, Radical Scavenging and General Toxicity Activities
عنوان لاتین مقاله Essential Oil from Flowers and Leaves of Elaeagnus Angustifolia (Elaeagnaceae): Composition, Radical Scavenging and General Toxicity Activities
ناشر 3
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت http://apb.tbzmed.ac.ir/Portals/0/Archive/Vol6-2016/23-Heshmati-Afshar.pdf

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Purpose: The aim of this work was to identify the chemical composition of the essential oils obtained from the flowers and leaves of Elaeagnus angostifolia (Elaeagnaceae) along with evaluate the radical scavenging and general toxicity activities. Methods: A combination of GC-MS and GC-FID were utilized for analyzing the chemical profile of the essential oils extracted by hydro-distillation from the leaves and flowers of E. angustifolia. The essential oils were subjected to general toxicity and radical scavenging assays using brine shrimp lethality test and DPPH method, respectively. Results: In total, 53 and 25 components were identified and quantified in the essential oils of flowers and leaves, accounting for 96.59% and 98.97% of the oil, respectively. The both oils were observed to be rich in ester compounds. The most abundant components of the oil from flowers were E-ethyl cinnamate (60.00%), hexahydrofarnesyl acetone (9.99%), palmitic acid (5.20%) and phytol (3.29%). The major constituents of the oil from leaves were E-ethyl cinnamate (37.27%), phytol (12.08%), nonanal (10.74%) and Z-3-hexenyl benzoate (7.65%). Both oils showed moderate activity in DPPH assay; however, they exhibited potent tocixity in brine shrimp lethality test. Conclusion: The remarkable toxicity effects of the oils are worthy to further investigation to find the probable mechanisms of action accountable for the noticeable toxic effect of these essential oils

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نویسنده نفر چندم مقاله
محمدعلی تربتیاول
سولماز اثناعشریدوم
فریبا حشمتی افشارسوم

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2016-ABP-senjed.pdf1396/08/02564028دانلود