چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | حامد همیشه کار |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات کاربردی دارویی |
| کد مقاله | 61561 |
| عنوان فارسی مقاله | Vitamin A palmitate-bearing nanoliposomes: Preparation and characterization |
| عنوان لاتین مقاله | Vitamin A palmitate-bearing nanoliposomes: Preparation and characterization |
| ناشر | 5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | Food Bioscience |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://www.sciencedirect.com/science/article/pii/S2212429215300262 |
| The encapsulation of fat soluble vitamins in nanoliposomes seems to be an effective method for protecting them from light, oxygen and chemical degradation. In this study, nanoliposomes containing vitamin A palmitate were prepared from different concentrations of lecithin–cholesterol (60:0, 50:10, 40:20 and 30:30 mg) by thin-film hydration–sonication method. Fourier transform infrared spectra (FTIR) were utilized to study the possible bioactive–lipid complex formation and the results indicated that the complex between vitamin A and liposomes were formed by physical interaction. Particle size, morphology, encapsulation efficiency and physical stability tests were carried out to determine the physicochemical properties of the resulted vitamin A-bearing liposomes. The size of particles were in the range of 76–115 nm and the particle size distributions were monomodular (span=0.6–0.88). The results showed that using the highest cholesterol concentration for preparing of liposomes containing vitamin A palmitate induces lower encapsulation efficiency and 50/10 mg lecithin–cholesterol concentration was used for preparation of optimum formulation of vitamin A palmitate-loaded nanoliposomes with mean size of about 76 nm and monomodular size distribution (span=0.74) and the encapsulation efficiency was 15.8%. |
| نویسنده | نفر چندم مقاله |
|---|---|
| اکرم پزشکی | اول |
| حامد همیشه کار | سوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 2016-Pezeshki-Food Bioscience.pdf | 1396/07/21 | 998089 | دانلود |
