Histological evaluation of follicular delivery of arginine via nanostructured lipid carriers: a novel potential approach for the treatment of alopecia
Histological evaluation of follicular delivery of arginine via nanostructured lipid carriers: a novel potential approach for the treatment of alopecia
نویسندگان: حامد همیشه کار , مریم کوه سلطانی , خسرو ادیب کیا
کلمات کلیدی: Arginine, alopecia, nanostructured lipid carriers, dermal drug delivery, NLC
نشریه: , 7 , 45 , 2017
| نویسنده ثبت کننده مقاله |
حامد همیشه کار |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات کاربردی دارویی |
| کد مقاله |
61554 |
| عنوان فارسی مقاله |
Histological evaluation of follicular delivery of arginine via nanostructured lipid carriers: a novel potential approach for the treatment of alopecia |
| عنوان لاتین مقاله |
Histological evaluation of follicular delivery of arginine via nanostructured lipid carriers: a novel potential approach for the treatment of alopecia |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
Artificial Cells, Nanomedicine, and Biotechnology |
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
http://www.tandfonline.com/doi/pdf/10.1080/21691401.2016.1241794?needAccess=true |
| The use of lipidic nanoparticles can overcome the limitations of skin penetration of hydrophilic charged materials. Oleic acid as an ion pairing agent was used to enhance the encapsulation of positively charged arginine into lipophilic nanostructured lipid carrier (NLC). Histological study on the male hamsters was performed to assess the efficiency of drug delivery on hair growth. The accumulation of NLCs in the hair follicles was verified and in vivo studies showed more new hair follicle growth by utilizing arginine-loaded NLCs than arginine aqueous solution. It was concluded that employing ion pairing agent could enhance drug encapsulation into NLCs structure. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Histological evaluation of follicular delivery of arginine via nanostructured lipid carriers a novel potential approach for the treatment of alopecia.pdf | 1396/07/19 | 3669666 | دانلود |