چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | سویل حکیمی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پرستاری و مامائی |
| کد مقاله | 61534 |
| عنوان فارسی مقاله | The effect of prebiotic vaginal gel with adjuvant oral metronidazole tablets on treatment and recurrence of bacterial vaginosis: a triple‑blind randomized controlled study |
| عنوان لاتین مقاله | The effect of prebiotic vaginal gel with adjuvant oral metronidazole tablets on treatment and recurrence of bacterial vaginosis: a triple‑blind randomized controlled study |
| ناشر | 7 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | Arch Gynecol Obstet |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://link.springer.com/journal/404 |
| in SPSS-21 using Chi square, repeated measures, and student’s t tests at a significance level of P < 0.05. Results The results obtained showed no significant difference between the two groups in terms of personal and social characteristics, clinical complaints, or laboratory markers. On the 10th day, healing rate based on Amsel and Nugent criteria was 76% in the intervention group and 30% in the control group [odds ratio (OR) 4.3; 95% confidence interval (CI) 2.7–9.4]. On the 90th day, healing rate was 84% in the intervention group and 62% in the control group (OR 3.7; 95% CI 1.3–8.9). Conclusions Adjuvant treatment with prebiotic vaginal gel improves the efficacy of bacterial vaginosis treatment. Keywords Prebiotic · Bacterial vaginosis · Amsel criteria · Nugent criteria · Recurrence Abstract Purpose Bacterial vaginosis is a change in the normal vaginal bacterial flora that leads to loss of hydrogen peroxide producing lactobacilli and overgrowth of predominantly anaerobic bacteria. The present study was conducted to compare the effects of prebiotic vaginal gel with oral metronidazole tablet and metronidazole tablet alone on treatment and recurrence of bacterial vaginosis. Methods The present triple-blind randomized clinical trial was conducted in Sadatmandi Hospital in Robat-Karim town, where 100 patients were randomly divided into intervention (receiving a 5 mg prebiotic vaginal gel applicator plus three 250 mg metronidazole tablets per day for 7 days) and control (receiving a 5 mg placebo vaginal gel applicator and three 250 mg metronidazole tablets per day for 7 days) groups. Then, patients were assessed for bacterial vaginosis on 90 ± 3 day after treatment. Data collected were analyzed * |
| نویسنده | نفر چندم مقاله |
|---|---|
| سویل حکیمی | اول |
| عزیزه فرشباف خلیلی | سوم |
| پروین دهقان | چهارم |
| یوسف جوادزاده | پنجم |
| شمسی عباسعلیزاده | ششم |
| باقر خلوتی | هفتم |
| فرانک فرهان | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 10.1007%2Fs00404-017-4555-x.pdf | 1396/07/15 | 1234712 | دانلود |
