Effect of sesame seed on lipid profile and redox status in hyperlipidemic patients
Effect of sesame seed on lipid profile and redox status in hyperlipidemic patients
نویسندگان: بیت الله علیپور , مهدیه خادم حقیقیان , بینا افتخارسادات , محمد اصغری جعفرآبادی
کلمات کلیدی: Keywords: hyperlipidemic patient, lipid profile, oxidative stress, sesame seed
نشریه: 15145 , 6 , 63 , 2012
| نویسنده ثبت کننده مقاله |
بینا افتخارسادات |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پزشکی ,طب فیزیکی وتوانبخشی |
| کد مقاله |
61531 |
| عنوان فارسی مقاله |
Effect of sesame seed on lipid profile and redox status in hyperlipidemic patients |
| عنوان لاتین مقاله |
Effect of sesame seed on lipid profile and redox status in hyperlipidemic patients |
| ناشر |
4 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
https://www.researchgate.net/profile/Mohammad_Asghari_Jafarabadi/publication/221765075_Effect_of_sesame_seed_on_lipid_profile_an |
| Pre-clinical studies suggest that sesame and its lignans induce beneficial changes in risk factors related to cardiovascular disease.
This study was designed to investigate the effects of sesame on reducing serum lipids and enhancing antioxidant capacity in 38
hyperlipidemic patients who were divided into two groups randomly. For all individuals along the 60 days of study period, the
same drug treatments were considered. Intervention group patients were supposed to eat 40 g white sesame seeds daily, and
instead of these calories, 240 kcal was removed from their diet. Anthropometric measurements including height, weight and
body mass index (BMI) were measured. We assessed lipid profile and oxidative stress indicators such as glutathione peroxidase
(GPX), superoxide dismutase (SOD) and thiobarbituric acid reactive substances (TBARS) before and after the intervention.
Significant differences among and between the groups were determined by independent t-test and paired sample t-test using
13th version of statistical package for the social sciences. The results showed that the diet with sesame significantly decreased the
levels of serum total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and TC/HDL-C ratio. Lipid
peroxidation (TBARS) decreased while the activities of GPX and SOD were increased. There were no significant changes in
anthropometric indexes such as weight and BMI after consumption of sesame. The results suggested that sesame seed
supplementation decreased serum TC, LDL-C and lipid peroxidation, and increased antioxidant status in hyperlipidemic
patients. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| seasum seed.pdf | 1396/07/15 | 155556 | دانلود |