چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | رضا قوطاسلو |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات ایمونولوژی |
| کد مقاله | 61459 |
| عنوان فارسی مقاله | Antibiotic Resistance Patterns of Biofilm-Forming Pseudomonas Aeruginosa Isolates from Mechanically Ventilated Patients |
| عنوان لاتین مقاله | Antibiotic Resistance Patterns of Biofilm-Forming Pseudomonas Aeruginosa Isolates from Mechanically Ventilated Patients |
| ناشر | 5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | International Journal of Scientific Study |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | International Journal of Scientific Study |
| Introduction: Pseudomonas aeruginosa (P. aeruginosa) is one of the most commoncauses of difficult-to-treat lung infections. The aim of study wasto evaluate susceptibility patterns of biofilm-forming P. aeruginosa atmechanically ventilated patients. Materials & Methods: Totally,50 P. aeruginosa isolates obtained from endotracheal aspirate specimensin patients of cardiosurgical intensive care unitswho were intubated for more than 48h. Detection of biofilm-forming carried out by tube and microtitre assaysandsusceptibility testing was performed by Kirby-Bauer method. Results: Resistance to piperacillin, gentamicin, ciprofloxacin, aztreonam, ceftizoximeand levofloxacin has been more than 60%. Resistance to colistinwas not seen.Multidrug resistant (MDR) was detected in 65% of the isolates. In the present study, 28 of 50(56%) and 19 of 50 (38%) isolates were biofilm-forming by microtitreand tube methods, respectively. Overall,biofilm-forming isolates were more resistant than non-biofilm-forming P. aeruginosa to antibiotics. The biofilm formation was significantly higher instrains that were MDR(p < 0.05). Conclusion: Themost effective drug against P. aeruginosawas colistin, followed by carbapenems, amikacin and cefepime.P. aeruginosa biofilms were extensively more resistant to furthermost antibiotics tested. Therefore, biofilm formation may need more attention when antibiotic treatment is selected for intubated patients. |
| نویسنده | نفر چندم مقاله |
|---|---|
| محمد یوسف معمار | دوم |
| ناصر علی زاده | سوم |
| ناصر صفائی آغبلاغ | چهارم |
| مینا یکانی | اول |
| رضا قوطاسلو | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| ijss_YEKANI Pseudoreza__aug_oa26_20170812_v0.pdf | 1396/07/01 | 608954 | دانلود |
| Doc1.docx | 1396/07/01 | 130779 | دانلود |
