چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | رضا قوطاسلو |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات ایمونولوژی |
| کد مقاله | 61388 |
| عنوان فارسی مقاله | Mycobacterium Tuberculosis Diversity by Exact Tandem Repeats-Variable Number Tandem Repeat Method in Azerbaijan, Iran |
| عنوان لاتین مقاله | Mycobacterium Tuberculosis Diversity by Exact Tandem Repeats-Variable Number Tandem Repeat Method in Azerbaijan, Iran |
| ناشر | 5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | Infectious Diseases in Clinical Practice |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://journals.lww.com/infectdis/Abstract/2016/07000/Detection_of_Virulence_Genes_in_Enterococci.9.aspx |
| Background: Tuberculosis (TB) is the leading cause of adult deaths among infectious agents. One of the genetic fingerprinting techniques to study the epidemiology of TB is variable number tandem repeat (VNTR). The purpose of this study was to determine the diversity of Mycobacterium tuberculosis isolated from patients in Azerbaijan, Iran by exact tandem repeats (ETR)-VNTR method. Methods: We used the ETR-VNTR method to analyze the genotypes of M. tuberculosis isolates. Forty-seven isolates were collected from pulmonary and extra pulmonary Tuberculosis patients associated with epidemiological data such as human immunodeficiency virus, anti-TB drugs use, cigarette smoking, diabetesmellitus, lung cancer, contact with TB patients, Bacillus Calmette–Guérin vaccine use, cough, housekeeping, fever, and other risk factors from April 2013 to February 2015 in Tabriz Research Center of Tuberculosis and Lung Disease. Three loci ETR-A, ETR-B, and ETR-C of VNTR patterns were studied. The patients' data were checked to determine the relationships between the epidemiological data and M. tuberculosis diversities. Results: Among the 47 isolates, 45 separate ETR-VNTR patterns consist of 9 clusters, 24 nonclusters (unique patterns) were found. No locus was observed in 2 samples. Diabetes and close household contacts were identified as important risk factors for TB in our subjects with unique patterns. Conclusions: Thirty-three distinct patterns were distinguished. In the case of respiratory symptoms in patientswith diabetes and close household contact patients, TB can be considered as the important differential diagnosis with unique patterns. |
| نویسنده | نفر چندم مقاله |
|---|---|
| سید رضا مودب | دوم |
| رضا قوطاسلو | پنجم |
| محمد اصغرزاده | سوم |
| ناصر علی زاده | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 10.1097@IPC.0000000000000561.pdf | 1396/07/15 | 197001 | دانلود |
