Effects of Helicobacter pylori treatment on rosacea: A single-arm clinical trial study
Effects of Helicobacter pylori treatment on rosacea: A single-arm clinical trial study
نویسندگان: پرویز صالح , محمد نقوی بهزاد , حمیده هریزچی قدیم , محمد میرزا آقازاده عطاری , رضا پیری
کلمات کلیدی: Key words: eradication, Helicobacter pylori, prevalence, rosacea, treatment.
نشریه: 55302 , 1 , 1 , 2017
| نویسنده ثبت کننده مقاله |
محمد نقوی بهزاد |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
کمیته تحقیقات دانشجویی |
| کد مقاله |
61297 |
| عنوان فارسی مقاله |
Effects of Helicobacter pylori treatment on rosacea: A single-arm clinical trial study |
| عنوان لاتین مقاله |
Effects of Helicobacter pylori treatment on rosacea: A single-arm clinical trial study |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
http://onlinelibrary.wiley.com/doi/10.1111/1346-8138.13878/full |
| Rosacea is a chronic dermatological disease. Helicobacter pylori has been discussed as one of its causative factors.
In this clinical trial study, we attempted to evaluate the effect of H. pylori standard eradication protocol on
the rosacea clinical course. In this single-arm clinical trial, patients ascertained to have H. pylori infection based
on serological studies were assessed to examine existence of rosacea. Patients with concurrent rosacea and
H. pylori infection were included in the study and underwent standard H. pylori eradication therapy. Rosacea was
evaluated using the Duluth rosacea grading score at the beginning, 2 months later and at the end of the trial (day
180). Of 872 patients positive for H. pylori, 167 patients (19.15%) manifested the clinical features of rosacea. The
patients with concurrent rosacea were younger (P < 0.001) and with a female sex predominance (P = 0.03) when
compared with rosacea-free patients. Of 167 patients, 150 received H. pylori eradication therapy, demonstrating a
92% (138/150) cure rate. The rosacea Duluth score grading on day 0, 60 and 180 among 138 patients significantly
decreased in most of the criteria except for telangiectasias (P = 0.712), phymatous changes (P = 0.535) and the
existence of peripheral involvement (P = 0.431). The present study concluded that H. pylori eradication leads to
improvement of rosacea. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Published.pdf | 1396/06/01 | 148154 | دانلود |
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| 4.pdf | 1396/06/02 | 156812 | دانلود |
| payaname.pdf | 1396/06/02 | 2919658 | دانلود |