چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | اکبر غلام پور |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده بهداشت |
| کد مقاله | 61249 |
| عنوان فارسی مقاله | Bioaerosol exposure and circulating biomarkers in a panel of elderly subjects and healthy young adults |
| عنوان لاتین مقاله | Bioaerosol exposure and circulating biomarkers in a panel of elderly subjects and healthy young adults |
| ناشر | 14 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://cyber.sci-hub.bz/MTAuMTAxNi9qLnNjaXRvdGVudi4yMDE3LjAzLjE4Ng==/10.1016%40j.scitotenv.2017.03.186.pdf |
| Numerous studies have found that risk of cardiovascular diseases is associatedwith increased blood levels of circulating markers of systemic inflammation.We investigated associations of acute exposure to bioaerosols (bacteria and fungi)with blood markers of inflammation and coagulation using panels of elderly subjects and healthy young adults. We conducted a panel study of 44 nonsmoker elderly subjects in a retirement communities and a panel study of 40 healthy young adults living in a school dormitory within Tehran city, Iran. Blood sample biomarkerswere measuredweekly over 6 weeks and including high sensitive C-reactive protein (hsCRP), tumor necrosis factor-soluble receptor-II (sTNF-RII), von Willebrand factor (vWF), white blood cells (WBC) count and interleukin-6 (IL-6). We found significant positive associations for IL-6 and WBC with exposure to Aspergillus spp. (As), Cladosporium spp. (Cl), Penicillium spp. (Pe), total fungi (TF) and Micrococcus spp. (MI); vWF with Cl andMI; sTNF-RII with Staphylococcus spp. (ST) in healthy young adults from the current-day and multiday averages. For elderly subjects, we observed significant positive associations for hsCRP, sTNF-RII and WBC with exposure to MI, but not with ST and total bacteria (TB). Our results showed the strongest significant positive associations for IL-6 with MI, ST and TB in elderly people. In addition, IL-6 was also positively associated with As, Cl and Pe in elderly. Also, the results showed that increase of vWF was significantly associated with bacterial and fungal aerosols, except Bacillus spp. (BA) at some lags in elderly subjects. Pooled results support the pivotal role of bioaerosols in increasing the level of some of inflammatory biomarkers, especially IL-6 andWBC in healthy young adults but possibly also in elderly people. |
| نویسنده | نفر چندم مقاله |
|---|---|
| اکبر غلام پور | دهم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Bioaerosol exposure and circulating biomarkers in a panel of elderly.pdf | 1396/05/25 | 801385 | دانلود |
