چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | فرناز منجم زاده |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده داروسازی |
| کد مقاله | 61183 |
| عنوان فارسی مقاله | Evaluation of activation energy conformity derived from modelfree non-isothermal predictions and Arrhenius isothermal results |
| عنوان لاتین مقاله | Evaluation of activation energy conformity derived from modelfree non-isothermal predictions and Arrhenius isothermal results |
| ناشر | 5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://link.springer.com/content/pdf/10.1007%2Fs10973-017-6279-3.pdf |
| Abstract In this study, the activation energy of HCTZ– lactose interaction was determined and compared to isothermal and non-isothermal methods. DSC data were fitted to different thermal models such as Friedman, Flynn– Wall–Ozawa and Kissinger–Akahira–Sunose, and the activation energy was calculated subsequently. Isothermal studies were performed by heat ovens, and analysis was done using high-performance liquid chromatography technique, and the activation energy (Ea) were calculated according to Arrhenius method. To date, no practical evaluations has been performed in the literature on the conformity of these different heating methods in incompatibility studies. The kinetic data obtained from the isothermal and non-isothermal methods showed no significant difference. The current study demonstrated a good conformity between the isothermal and non-isothermal kinetic results, and thus, it can be suggested that DSCbased kinetic analysis can provide a simple, reliable and fast comparative data in the kinetic evaluation of an incompatibility seen in early stages of preformulation studies. Finally, the advantages and drawbacks of each method are fully discussed. |
| نویسنده | نفر چندم مقاله |
|---|---|
| محبوب نعمتی | دوم |
| فرناز منجم زاده | پنجم |
| محمد رضا سیاهی شادباد | سوم |
| هادی ولیزاده | چهارم |
| فرانک قادری | اول |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| HCTZ Arhenious.pdf | 1396/05/18 | 1461414 | دانلود |
| Ghaderi sabt.doc | 1396/05/18 | 86016 | دانلود |
