Liposome-based drug co-delivery systems in cancer cells
Liposome-based drug co-delivery systems in cancer cells
نویسندگان: سپیده زنونی واحد , رویا صالحی قره ورن , سودابه داوران , سیمین شریفی
کلمات کلیدی: Liposome : Co-delivery :Combination therapy: Chemotherapy: Cancer treatment
نشریه: 23450 , - , 71 , 2017
| Combination therapy and nanotechnology offer a promising therapeutic method in cancer treatment. By improving
drug's pharmacokinetics, nanoparticulate systems increase the drug's therapeutic effectswhile decreasing its
adverse side effects related to high dosage. Liposomes are extensively used as drug delivery systems and several
liposomal nanomedicines have been approved for clinical applications. In this regard, liposome-based combination
chemotherapy (LCC) opens a novel avenue in drug delivery research and has increasingly become a significant
approach in clinical cancer treatment. This review paper focuses on LCC strategies including co-delivery of:
two chemotherapeutic drugs, chemotherapeutic agent with anti-cancer metals, and chemotherapeutic agent
with gene agents and ligand-targeted liposome for co-delivery of chemotherapeutic agents. Definitely, the multidisciplinary
method may help improve the efficacy of cancer therapy. An extensive literature review was performed
mainly using PubMed |
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تاریخ درج فایل |
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دانلود |
| 40-Sharifi, Material Science and Engineering C, 2016.pdf | 1396/05/12 | 1127556 | دانلود |