عامل نروتروفیک مشتق از مغز در زنان چاق و ارتباط آن با لپتین و گرلین
Brain-derived neurotrophic factor in obese women and its relationship with leptin and ghrelin
نویسندگان: ثریا خیروری , شیرین حقیقی , اتوسا سعیدپور
کلمات کلیدی: obesity, BDNF, leptin, ghrelin
نشریه: 28307 , 2 , 19 , 2017
| نویسنده ثبت کننده مقاله |
ثریا خیروری |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده تغذیه |
| کد مقاله |
60995 |
| عنوان فارسی مقاله |
عامل نروتروفیک مشتق از مغز در زنان چاق و ارتباط آن با لپتین و گرلین |
| عنوان لاتین مقاله |
Brain-derived neurotrophic factor in obese women and its relationship with leptin and ghrelin |
| ناشر |
3 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
www.mattioli1885journals.com/index.php/progressinnutrition/article/view/ |
| Summary. Objectives: We aimed to assess the brain-derived neurotrophic factor (BDNF) level and its relation
with leptin and ghrelin levels in obese women. Methods: In this case-control cross-sectional study, forty obese
women and 40 healthy normal weight women aged (20- 50 y) were participated. Anthropometric indices
were measured and serum levels of BDNF, leptin and ghrelin were assessed by the ELISA method. Results:
Obese women had significantly higher leptin, but lower ghrelin levels compared with normal weight women.
BDNF level was comparable between the two groups of women. There was a strong positive correlation between
leptin and anthropometric parameters. A significant negative association was found between BDNF
and leptin levels in normal weight women (r= -0.41, p= 0.02). Conclusion: Our results in women do not support
a relationship between BDNF and obesity. Anthropometric indices may be important predictors of the
leptin level. Further studies are required to elucidate the exact link between BDNF and leptin. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| haghighi.pdf | 1396/04/21 | 1157283 | دانلود |