چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | علیرضا قراتپه |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | کمیته تحقیقات دانشجویی |
| کد مقاله | 60931 |
| عنوان فارسی مقاله | نانوذرات طلای مهندسی شده برای درمان فتوترمال تراپی سرطان و کشتن باکتری ها |
| عنوان لاتین مقاله | Engineered gold nanoparticles for photothermal cancer therapy and bacteria killing |
| ناشر | 4 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Review Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://pubs.rsc.org/En/content/articlelanding/2016/ra/c6ra18760a#!divAbstract |
| Over recent decades, one of the most important and complex problems facing our society is the multi-drug resistance of human cancer cells and pathogens to most clinically approved therapeutics. Recent advances in nanoscience and nanotechnology have expanded our ability to design and construct nanomaterials with targeting, therapeutic, and diagnostic functions. These multifunctional materials have gained attention as promising tools for selective cancer/bacteria therapy in the absence of current drugs. Photothermal therapy (PTT) is a minimally invasive therapy in which photon energy is converted into heat in order to kill cancer cells. Gold nanoparticles (GNPs) with a high light-to-heat conversion capability are among the most important candidates for PTT. GNP-assisted PTT has shown great success in recent years, suggesting promise for future applications. In this review, we will discuss the current status of GNPs in the photothermal treatment of cancer and bacterial conditions. The review starts with an outline of recent developments in the various methods used for the size- and shape-controlled synthesis of GNPs, followed by a discussion of the modification of GNPs using suitable protecting and functionalizing agents. We will then consider therapeutic outcomes of different types of GNP-assisted PTT in cancer therapy and bactericide through a comprehensive review of the most important results obtained both in vivo and in vitro. The advantages and disadvantages of methods for developing different-shaped GNPs, variations in irradiation conditions, the use of PTT in combination with other therapeutic methods, and a comparison between the PTT efficacies of different-shaped GNPs will also be discussed in detail |
| نویسنده | نفر چندم مقاله |
|---|---|
| سودابه داوران | دوم |
| رویا صالحی قره ورن | سوم |
| حامد همیشه کار | چهارم |
| علیرضا قراتپه | اول |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| c6ra18760a.pdf | 1396/04/11 | 3182336 | دانلود |
| IF page.jpg | 1396/04/27 | 111504 | دانلود |
