چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | احد باویلی تبریزی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده داروسازی |
| کد مقاله | 60572 |
| عنوان فارسی مقاله | DETERMINATION OF TRIAMTERENE IN HUMAN PLASMA AND URINE AFTER ITS CLOUD POINT EXTRACTION |
| عنوان لاتین مقاله | DETERMINATION OF TRIAMTERENE IN HUMAN PLASMA AND URINE AFTER ITS CLOUD POINT EXTRACTION |
| ناشر | 7 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://dx.doi.org/10.5935/0100-4042.20140188 |
| A new analytical approach was developed involving cloud point extraction (CPE) and spectrofluorimetric determination of triamterene (TM) in biological fluids. A urine or plasma sample was prepared and adjusted to pH 7, then TM was quickly extracted using CPE, using 0.05% (w/v) of Triton X-114 as the extractant. The main factors that affected the extraction efficiency (the pH of the sample, the Triton X-114 concentration, the addition of salt, the extraction time and temperature, and the centrifugation time and speed) were studied and optimized. The method gave calibration curves for TM with good linearities and correlation coefficients (r) higher than 0.99. The method showed good precision and accuracy, with intra- and inter-assay precisions of less than 8.50% at all concentrations. Standard addition recovery tests were carried out, and the recoveries ranged from 94.7% to 114%. The limits of detection and quantification were 3.90 and 11.7 μg L−1, respectively, for urine and 5.80 and 18.0 μg L−1, respectively, for plasma. The newly developed, environmentally friendly method was successfully used to extract and determine TM in human urine samples. |
| نویسنده | نفر چندم مقاله |
|---|---|
| احد باویلی تبریزی | اول |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| TM(quim nova).pdf | 1396/02/06 | 367032 | دانلود |
