Assessing Absorption Coefficient of Hemoglobin in the Breast Phantom Using Near-Infrared Spectroscopy

Assessing Absorption Coefficient of Hemoglobin in the Breast Phantom Using Near-Infrared Spectroscopy


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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: پریناز محنتی

کلمات کلیدی: Hemoglobin, Optical Properties, Near Infrared Spectroscopy, Absorption Coefficient

نشریه: , Published online 2016 June 25. , Published online 2016 June 25. , 2015

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نویسنده ثبت کننده مقاله پریناز محنتی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده پزشکی
کد مقاله 60505
عنوان فارسی مقاله Assessing Absorption Coefficient of Hemoglobin in the Breast Phantom Using Near-Infrared Spectroscopy
عنوان لاتین مقاله Assessing Absorption Coefficient of Hemoglobin in the Breast Phantom Using Near-Infrared Spectroscopy
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق) Iranian Journal of Radiology
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت doi: 10.5812/iranjradiol.31581.

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Background: Blood concentrations and oxygen saturation levels are important biomarkers for breast cancer diagnosis. Objectives: In this study, the absorption coefficient of hemoglobin (Hb) was used to distinguish between normal and abnormal breast tissue Materials and Methods: A near-infrared source (637 nm) was transmitted from major and minor vessels of a breast phantom containing 2, 4 concentrations of oxy- and deoxy-Hb. The absorption coefficients were determined from spectrometer (SM) and powermeter (PM) data. Results: The absorption coefficients were 0.075  0.026 cm-1 for oxygenated Hb (normal) in major vessels and 0.141  0.023 cm-1 at 4 concentration (abnormal) with SM, whereas the breast absorption coefficients were 0.099  0.017 cm-1 for oxygenated Hb (normal) in minor vessels and 0.1710.005 cm-1 at 4concentrations with SM. A comparison of the data obtained using a SM and a PM was not significant statistically. Conclusion: The study of the absorption coefficient data of different concentrations of Hb in normal and abnormal breasts via the diffusion of near-infrared light is a valuable method and has the potential to aid in early detection of breast abnormalities with SM and PM in major and minor vessels.

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پریناز محنتیاول

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