چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | شیرین فتاحی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده دندانپزشکی |
| کد مقاله | 60471 |
| عنوان فارسی مقاله | Configuring the Expression of Wilms Tumor 1 in Oral Squamous Cell Carcinoma and its Relationship with Clinicopathologic Features |
| عنوان لاتین مقاله | Configuring the Expression of Wilms Tumor 1 in Oral Squamous Cell Carcinoma and its Relationship with Clinicopathologic Features |
| ناشر | 4 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | Journal of Dental Applications |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح چهار – سایر سایت های تخصصی |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://www.austinpublishinggroup.com/dental-applications/fulltext/jda-v3-id1086.php |
| Introduction: The most common oral cancer is Squamous Cell Carcinoma (SCC) that a wide variety of environmental factors has caused complex etiology in terms of prevalence presentation also a significant correlation between the levels of WT1 expression and prognosis of the disease has been reported. Materials and Methods: For This descriptive - analytical study samples were collected from the archives of Pathology Department of Imam Reza Hospital Tabriz and Department of Pathology of Dentistry School. In this study, data from patients’ records and results of Immunohistochemical staining (IHC) were collected in the laboratory. After a review of the histopathologic grade we compared them with the data records to ensure the accuracy grade and then were compared with the results of immunohistochemistry. Chi-square test and comparison of independent groups was analyzed using statistical software spss16. Results: From 45 cases, expression of WT1 has been reported in 3 cases (6.2%) and all of them were well-differentiated. The mean age of the participants was 66.42 (±16.06) years, which 16 cases were female (35.6%) and 29 cases were male (64.6%). Histopathologic grade was well-differentiated in 36 cases (80%), 2 cases had poorly-differentiated grade (4/4%), and moderatelydifferentiation was reported in 7 cases (6.15%). There was not significant relation between histopathologic grade and WT1 expression. Conclusion: Further studies about investigating of the possibility of treatment with immunotherapy based WT1 peptide as an effective treatment in cases with increased expression of WT1, are suggested. |
| نویسنده | نفر چندم مقاله |
|---|---|
| سپیده وثوق حسینی | سوم |
| شیرین فتاحی | اول |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| fulltext_jda-v3-id1086.pdf | 1396/01/23 | 2717027 | دانلود |
