چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | محمد نقوی بهزاد |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات فلسفه و تاریخ پزشکی |
| کد مقاله | 60365 |
| عنوان فارسی مقاله | ارتباط درجه بافت شناختی تهاجم کارسینوم مهاجم مجرایی پستان و انفیلتراسیون ماست سل ها |
| عنوان لاتین مقاله | The relationship between histologic grades of invasive carcinoma of breast ducts and mast cell infiltration |
| ناشر | 6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | South Asian Journal of Cancer |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح دو – PubMed |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://www.ncbi.nlm.nih.gov/pubmed/27169108 |
| Introduction: Breast carcinoma isthe most prevalenttumors among women. Transformation of inflated cellsin immune response leadsto increase in inflammatory cellssuch as macrophages,mast cells (MC) and fibroblasts.The aim ofthisstudy wasto determine the relationship between grades of invasive carcinoma ofthe breast ducts and MC infiltration around tumoral cells. Methods: During the present study, 75 female patients suffering from invasive ductal carcinoma who underwent surgery or diagnostic biopsy during 2010 and 2013 in Educational‑Medical centers of Tabriz University of Medical Sciences, were included in the study. Based on Bloom‑Richardson grading system, 25 cases were selected from each grade. To better observe of MCs, samples were stained by Toluidine blue and MCs were counted in 10 40 × 10 fields.Results: The mean age was 47.56 ± 10.84 and the number of MCs was between 6 and 96 and their overall average was 43.01. Average count of MCs in grade 1, 2 and 3 were 15.92 ± 10.07, 45.32 ± 10.47, and 67.8 ± 20.70,respectively.There was a significant relationship between the number of MCs and increase in disease grade (P < 0.001).With increasing grade of malignancy,the number of MCs had grown.No significant relationship was observed between age and grade of disease or age and number of MC. Conclusion:According to obtained results, number of MC around tumoral cells increased significantly with an increase in the grade of disease. In order to treat in the first stages of the disease,recognizing primary changes in the stroma of cells could be helpful. |
| نویسنده | نفر چندم مقاله |
|---|---|
| اشرف فخرجو | اول |
| محمد نقوی بهزاد | دوم |
| وحید منتظری | سوم |
| فرید کارکن شایان | چهارم |
| لیلا نوروزی-پناهی | پنجم |
| رضا پیری | ششم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| SouthAsianJCancer53166-9430271_023710.pdf | 1395/12/24 | 286563 | دانلود |
| SouthAsianJCancer_2016_5_1_5_179699.pdf | 1395/12/24 | 1252155 | دانلود |
| 1.png | 1396/12/09 | 140570 | دانلود |
| Form.pdf | 1396/01/26 | 397729 | دانلود |
