چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | محمد رضا اردلان |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات کلیه |
| کد مقاله | 60294 |
| عنوان فارسی مقاله | Relationship of Serum Klotho Level With ACE Gene Polymorphism in Stable Kidney Allograft Recipients |
| عنوان لاتین مقاله | Relationship of Serum Klotho Level With ACE Gene Polymorphism in Stable Kidney Allograft Recipients |
| ناشر | 6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://www.ncbi.nlm.nih.gov/pubmed/28270648 |
| Introduction. The kidney is the main source of serum Klotho production. Immunosuppressive agents could affect the kidney in this regard. The effect of the ACE gene polymorphism on Klotho production is a less studied area. This study aimed to assess serum Klotho and ACE gene in a group of stable kidney transplant recipients. Materials and Methods. In a cross-sectional study, 30 kidney transplant recipients with stable allograft function and 27 healthy young individuals were assessed for their serum Klotho levels. The ACE gene polymorphisms were studied in both groups. Results. Klotho level was higher in kidney transplant recipients than the controls, but the difference was not significant (2.76 ± 2.41 ng/mL versus 2.01 ± 1.41 ng/mL, respectively). In both groups, serum Klotho level was higher in those with the I>I polymorphism, the men, those with higher glomerular filtration rate, and younger individuals, but the differences did not reach a significant level. Higher body mass index was significantly associated with lower serum Klotho level in both groups. Conclusions. Klotho level after kidney transplantation meets the range in healthy individuals, and it is not affected by the ACE gene polymorphism. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مریم زارع نهندی | اول |
| محمد رضا اردلان | دوم |
| علی بناگذارمحمدی | سوم |
| امیر قربانی حق جو | چهارم |
| مرتضی جبارپور بنیادی | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Relationship of Serum Klotho Level With ACE Gene.pdf | 1395/12/18 | 375604 | دانلود |
