چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | محمد علی زاده |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده تغذیه |
| کد مقاله | 60262 |
| عنوان فارسی مقاله | Effect of Gundelia tournefortii L. extract on lipid profile and TAC in patients with coronary artery disease: A double-blind randomized placebo controlled clinical trial |
| عنوان لاتین مقاله | Effect of Gundelia tournefortii L. extract on lipid profile and TAC in patients with coronary artery disease: A double-blind randomized placebo controlled clinical trial |
| ناشر | 5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://www.sciencedirect.com/science/article/pii/S2210803316300045 |
| Effect of Gundelia tournefortii L. extract on lipid profile and TAC in Patients with Coronary Artery Disease: A double-blind randomized placebo controlled clinical trial Abstract Context: Gundelia tournefortii (GT) has been known to possess hypolipidemic and antioxidant activities. Objective: This study was carried out to evaluate the effects of GT on total antioxidant capacity (TAC) and lipid profile in patients with coronary artery disease (CAD). Materials and methods: A total of 38 angiographically confirmed CAD patients were enrolled in this randomized, double-blind, clinical trial. The subjects consumed G. tournefortii extract (GTE) or placebo for 8 consecutive weeks. Serum total cholesterol, triglyceride, high density lipoprotein-cholesterol (HDL-c), low density lipoproteincholesterol (LDL-c) and TAC were determined by conventional methods. In addition, dietary intake was recorded using 24-h recall method and converted into nutrients with software Nut4 version1. Results: At the end of the study, the GTE group had recorded a significantly lower energy intake compared to the placebo group (p=0.04). The BMI also significantly decreased in the GTE group by 3% (from 26.5±3.6 kg/m2 at baseline to 25.9±3.6 kg/m2 at the end of the trial). There was a significant reduction in total cholesterol level in the GTE group (151±23.8 mg/dl at baseline to 131.1±25.9 mg/dl at the end of the trial), however, its level increased slightly in the placebo group (133.5±22 mg/dl at baseline to 141.4±22.4 mg/dl at the end of the trial). The mean value of LDL-c level notably decreased in the GTE group from 86±26 to 60.58±29.9 mg/dl (p=0.001). No significant differences were observed in the groups for HDL-c or triglyceride levels; however, TAC significantly changed in the two groups after the intervention. Conclusion: The intervention resulted in a statistically significant difference in total cholesterol, LDL-c and BMI suggesting that GTE may be an appropriate adjunctive medicinal plant to help reduce the major risk factors of CAD. |
| نویسنده | نفر چندم مقاله |
|---|---|
| میرحسین سیدمحمدزاده | سوم |
| سعیده علیزاده سالطه | چهارم |
| ثریا خیروری | پنجم |
| محمد علی زاده | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Presentation1.jpg | 1396/04/22 | 59925 | دانلود |
