چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | مریم رف رف |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده تغذیه |
| کد مقاله | 60142 |
| عنوان فارسی مقاله | Pomegranate ( Punica granatum L. ) peel hydro alcoholic extract ameliorates cardiovascular risk factors in obese women with dyslipidemia : A double blind, randomized, placebo controlled pilot study |
| عنوان لاتین مقاله | Pomegranate ( Punica granatum L. ) peel hydro alcoholic extract ameliorates cardiovascular risk factors in obese women with dyslipidemia : A double blind, randomized, placebo controlled pilot study |
| ناشر | 6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | European journal of Integrative Medicine |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | Http:// dx.doi.org/10.1016/j.eujim.2016.06.010 |
| Introduction Dyslipidemia is one of the most important risk factors for cardiovascular disease. Previous studies have shown that pomegranate and its polyphenols may have hypolipidemic effects. The objective of this study was to evaluate the effects of pomegranate peel extract on some cardiovascular risk factors in patients with dyslipidemia. Methods Thirty eight obese women (30< body mass index (BMI) >35 kg/m2) with dyslipidemia were allocated into two groups receiving two 500 mg pomegranate peel extract (n = 19) or placebo (n = 19) daily for 8 weeks. Serum lipid profile (total cholesterol (TC), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), triglycerides (TG)), Blood Pressure(BP), serum high sensitive-C reactive protein (hs-CRP) and BMIwere measured. Results Pomegranate peel extract significantly decreased post treatment levels of serum TC (p = 0.014), LDL-C (p = 0.021), and TG (p = 0.036) and increased HDL-C (p = 0.020)compared to baseline. There was a significant decrease in Systolic Blood Pressure (SBP) levels and hs-CRP in pomegranate peel group whereas Diastolic Blood Pressure (DBP) levels and BMI remained unchanged after intervention. No significant changes were seen in terms of all post treatment values for the placebo group at the end of trial (p > 0.05). After adjusting for the baseline values, energy intake and weight changes, there were significant differences in post-treatment values between the two groups except in serum concentrations of HDL-C, DBP and BMI. Conclusions Current study showed a positive effect of pomegranate peel extract in improving cardiovascular risk factors in obese women with dyslipidemia. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهدیه خادم حقیقیان | اول |
| عبدالوهاب مقدم دیزج هریک | سوم |
| محمد اصغری جعفرآبادی | پنجم |
| بهرام پورقاسم گرگری | ششم |
| مریم رف رف | دوم |
| سالار همتی | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 1-s2.0-S1876382016301123-main-2.pdf | 1395/12/22 | 551869 | دانلود |
