| Abstract
Introduction: Hydration is necessary for surgery, and it is recommended that pre-operative
hydration may accompany with better outcome and shorter post-operative hospitalization. This
study aims at evaluating effects of pre-operative hydration on clinical outcome of patients
undergoing orthopedic surgery.
Methods: In this case-control study, 100 patients undergoing lower limb orthopedic surgery
were randomly classified as intervention group (pre-operative hydration, n = 50) and control
group (no pre-operative hydration, n = 50). The intervention group received crystalloid fluids
(ringer) 1.5 ml/kg during fasting, and the control group received no intravenous fluid before
surgery. Both groups were evaluated for intraoperative and post-operative findings.
Results: Comparing with the control group, the intervention group had significantly lower
hypotension during surgery (10 vs. 38%, P = 0.001), less hemodynamic disorder (8 vs. 30%,
P = 0.005), less need for pack cell transfusion (12 vs. 60%, P < 0.001), higher urine output
(1047.68 ± 586.78 vs. 750.36 ± 437.25 cc, P = 0.005), less intensive care unit (ICU) admission
(12 vs. 30%, P = 0.020), and shorter mean hospitalization (6.96 ± 1.78 vs. 8.96 ± 3.10 days,
P < 0.001). There was no significant difference between the groups considering mortality rate
(4 vs. 6%, P = 0.100).
Conclusion: Pre-operative hydration improves patient’s status during surgery, reduces
hypotension, and duration of hospitalization. |