Efficacy of Hypozalix spray and Propolis mouthwash for prevention of chemotherapy-induced oral mucositis in leukemic patients: A double-blindrandomized clinical trial

Efficacy of Hypozalix spray and Propolis mouthwash for prevention of chemotherapy-induced oral mucositis in leukemic patients: A double-blindrandomized clinical trial


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نویسندگان: حسین اسلامی , رامین نگاهداری , فیروز پور علی بابا , پریسا فلسفی , سپیده بهلولی , میلاد غنی زاده , بابک نجاتی

کلمات کلیدی: Artificial saliva, leukemia, mucositis, propolis, chemotherapy

نشریه: 19913 , 4 , 10 , 2016

اطلاعات کلی مقاله
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نویسنده ثبت کننده مقاله حسین اسلامی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده دندانپزشکی
کد مقاله 59841
عنوان فارسی مقاله Efficacy of Hypozalix spray and Propolis mouthwash for prevention of chemotherapy-induced oral mucositis in leukemic patients: A double-blindrandomized clinical trial
عنوان لاتین مقاله Efficacy of Hypozalix spray and Propolis mouthwash for prevention of chemotherapy-induced oral mucositis in leukemic patients: A double-blindrandomized clinical trial
ناشر 7
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح دو – PubMed
آدرس لینک مقاله/ همایش در شبکه اینترنت http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/3067/535

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Background. Oral mucositis is the chief complication of head and neck chemotherapy. This study was conducted to eva-luate Hypozalix artificial saliva and propolis mouthwash efficacy for the prevention of chemotherapy-induced oral mucosi-tis in leukemic patients. Methods. The present double-blind clinical trial was carried out on 72 patients undergoing chemotherapy. The patients were assigned to 3 groups. In the control group, CHX mouthwash and fluconazole were used by the subjects. In groups 1 and 2, Hypozalixand propolis mouthwashes were added to the combination therapy used in the control group. The results were compared between the three groups after 14 days. Results. Mean score A was significantly higher than mean score B in children (P=0.001). In contrast, mean score A was significantly lower than mean score B in young adults (P=0.003). Conclusion. Use of Hypozalixspray or propolis mouthwash in association with CHX mouthwash and fluconazole simulta-neously at the start of chemotherapy resulted in a decrease in chemotherapy complications after 14 days. In many cases the use of propolis mouthwash yielded better results and the patients exhibited a greater tendency to continue to use it.

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نویسنده نفر چندم مقاله
حسین اسلامیاول
رامین نگاهداریششم
فیروز پور علی بابادوم
پریسا فلسفیسوم
سپیده بهلولیچهارم
میلاد غنی زادههفتم
بابک نجاتیپنجم

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