چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | میترا نیافر |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات غدد درون ریز |
| کد مقاله | 59827 |
| عنوان فارسی مقاله | مقایسه آثار درمانی فنوفیبرات و ژم فیبروزیل بر پروفیل لیپیدی در بیماران دیابتی تیپ 2 |
| عنوان لاتین مقاله | The comparison of the therapeutic effect of fenofibrate and gemfibrozil on lipid profile in patients with type two diabetes |
| ناشر | 4 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | The Quarterly journal of School of Medicine, Shahid Beheshti University of Medical Sciences |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح چهار – سایر سایت های تخصصی |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://pejouhesh.sbmu.ac.ir/browse.php?a_id=1459&slc_lang=en&sid=1&ftxt=1 |
| Background: Diabetes is frequently along with hyperlipidemia. Glycemic control could improve this condition and including statins and fibrates is the best option to facilitate this amelioration. Noting the importance of diabetes in terms of its multiple complications and the load of its huge cost on the shoulders of the health system of our country, this study aimed to compare the efficacy of fenofibrate and gemfibrozil in improving lipid profile in patients with type II diabetes. Methods and materials: In this experimental setting, a total of 60 diabetic patients with serum low-density lipoprotein (LDL) in the target (p<0.001) range but with increased serum triglyceride were randomized in to 30-patient groups, receiving either fenofibrate (200 mg/day) or gemfibrozil (450 mg/day) for 3 consecutive months. Lipid profile changes at the endpoint were compared between the two groups with t-test Results: It seems except post treatment serum triglyceride level variations observed in two groups, which occurred to be significant. There was no significant difference in other analyzed parameters but there was a better improvement in serum lipid level in fenofibrate group. Conclusion: The efficacy of fenofibrate in improving serum lipid profile in diabetic patients is marginally better than that of gemfibrozil. |
| نویسنده | نفر چندم مقاله |
|---|---|
| میترا نیافر | اول |
| اکبر علی عسگرزاده | دوم |
| مجید مبصری | سوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Research in Medicine-v40n1p8-en.pdf | 1395/10/23 | 428812 | دانلود |
