چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | لیلا روشنگر |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پزشکی |
| کد مقاله | 59693 |
| عنوان فارسی مقاله | The Ovario-protective effect of erythropoietin against oxidative damage associated with reperfusion following ovarian torsion in rat |
| عنوان لاتین مقاله | The Ovario-protective effect of erythropoietin against oxidative damage associated with reperfusion following ovarian torsion in rat |
| ناشر | 9 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح سه – Scopus |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://thescipub.com/PDF/ajavsp.2011.18.24.pdf |
| Abstract: Problem statement: To show the effect of recombinant Erythropoietin (rhEPO) on the ovarian viability and histology in the twisted ischemic ovaries in rats, followed by detorsion. Approach: An experimental study was conducted in primate clinic of the School of Medicine, Tabriz University of Medical Sciences from Dec. 2008 to Apr. 2009. Forty, 4 month old Wistar rats are cased in the present study divided into 4 groups. Ovarian ischemia was performed by torsion which was kept stable by using a vascular microclip for 4 h. In group 1, the ovary were surgically removed, fixed and analyzed histochemically. In group 2, the same procedure was repeated after 3 h reperfusion. In the next two groups, the same was performed rhEPO was administrated 400 u kg−1 1 h after torsion of the ovaries. Results: Thirty-two out of 40 rats were followed. There was a significant difference between groups in the levels of Malondialdehyde (MDA), Total Antioxidants (TA), Superoxidase (SOD), Nitric Oxide (NO) glutathione ( p<0.001). Addition of rhEPO maintained the normal histologic appearance in interventional groups compared with controls. Conclusion: Administration of rhEPO was effective in reducing the ischemic effect and free radicals damages of ovarian torsion in rats. |
| نویسنده | نفر چندم مقاله |
|---|---|
| منیژه سیاح ملی | اول |
| مریم السادات کاظمی شیشوان | دوم |
| جعفر سلیمانی راد | سوم |
| محمدرضا رشیدی شاهگلی | چهارم |
| لیلا روشنگر | پنجم |
| نادره رشتچی زاده | ششم |
| مرتضی قوجازاده | هشتم |
| الهه اولاد صاحب مدارک | هفتم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| ajavsp.2011.18.24.pdf | 1395/10/08 | 297308 | دانلود |
