چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | لیلا روشنگر |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پزشکی |
| کد مقاله | 59643 |
| عنوان فارسی مقاله | ارزیابی اثر ضد باروری عصاره آبی سداب در موش ماده |
| عنوان لاتین مقاله | Antifertility effect of Ruta graveolens aqueous extract in female mice |
| ناشر | 4 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح سه – Scopus |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://phypha.ir/ppj/index.php?&slct_pg_id=10&sid=1&slc_lang=en |
| Background and purpose: Ruta Graveolens (RG) commonly called sudab, has been known as a medicinal plant since ancient times. Anti-oxidant, anti-inflammatory, anti-tumor, anti-androgenic, and anti-fertility activities are amongst the medicinal properties of RG. The present study investigated the antifertility effects of RG and in-vitro embryo development in female mice. Materials and methods: The study was performed in 30 female mice that were divided into two groups as control and RG. The control group received normal saline 0.2 ml and the RG group received 300 mg/kg aqueous extract of RG per day, orally for 14 days. Matured oocytes were transported to HTF+BSA (4mg/ml). Then fertilized oocytes, two cell, blastocyst and hatching embryos were evaluated. Results: In case group RG reduced embryo growth (P<0.05) at different stages. However, by disrupting RG administration no significant differences were observed between control and test animals. Conclusion: The results showed that the aqueous extract of RG decreased the embryo growth and fertilizing ability in female mice. Moreover, the negative impact of RG on fertilizing potential is recurrentable after disruption of exposure |
| نویسنده | نفر چندم مقاله |
|---|---|
| لیلا روشنگر | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| J Mazand Univ Med Sci-v24n117p133-en.pdf | 1395/10/02 | 238311 | دانلود |
