چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| علیرضا خبازی اسکویی | دوم |
| ابراهیم سخی نیا | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is an autosomal dominant periodic fever syndrome caused by mutations in the TNFRSF1A gene encoding the receptor for tumor necrosis factor (TNF)-α. It is characterized by attacks of prolonged episodes of fever, abdominal pain, severe myalgia, and painful erythema on the trunk or extremities. We report an 8 years child with febrile attacks used to occur every 1-2 month and continue for 3-4 days. During the attack patient had 40ºC fever without chill. About 80% of fever attacks were accompanied by abdominal manifestations. Genetic analysis showed a heterozygous R426L mutation in the exon 10 of TNFRSF1A gene. |
| کلمات کلیدی | Tumor Necrosis Factor Receptor-1 Associated Periodic Syndrome, Periodic fever syndrome, Mutation, Iranian |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| IMG_0003.jpg | 1395/08/01 | 605697 | دانلود |
| Invitation CSA poosters.pdf | 1395/08/01 | 143134 | دانلود |
