A comparison of the effect of triamcinolone ointment and mouthwash with or without zinc on the healing process of aphthous stomatitis lesions

A comparison of the effect of triamcinolone ointment and mouthwash with or without zinc on the healing process of aphthous stomatitis lesions


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دانشگاه علوم پزشکی تبریز
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نویسندگان: معصومه مهدی پور , علی تقوی زنوز , آذین سهرابی , نرگس قلیزاده , آیلا بهرامیان , زهرا جمالی

کلمات کلیدی: Aphthous stomatitis, zinc mouthwash, triamcinolone with orabase

نشریه: , 10 , 2 , 2016

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نویسنده ثبت کننده مقاله آیلا بهرامیان
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده دندانپزشکی
کد مقاله 58836
عنوان فارسی مقاله A comparison of the effect of triamcinolone ointment and mouthwash with or without zinc on the healing process of aphthous stomatitis lesions
عنوان لاتین مقاله A comparison of the effect of triamcinolone ointment and mouthwash with or without zinc on the healing process of aphthous stomatitis lesions
ناشر 6
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق) J Dent Res Dent Clin Dent Prospects
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح دو – PubMed
آدرس لینک مقاله/ همایش در شبکه اینترنت http://www.ncbi.nlm.nih.gov/pubmed/?term=A+comparison+of+the+effect+of+triamcinolone+ointment+and+mouthwash+with+or+without+zinc

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Background. Recurrent aphthous stomatitis (RAS) is one of the most common ulcerative diseases of the oral mucosa. De-finitive etiology of RAS has not been conclusively established. There is no certain treatment for aphthous stomatitis but some drugs such as steroids are commonly used for the treatment of RAS. Regarding the effect of zinc on the healing proc-ess of epithelial layer and cell division, in this research the effect of triamcinolone (with orabase) in combination with a zinc-containing mouthwash and triamcinolone alone on the healing process of RAS lesions was assessed. Methods. The present study consisted of 20 patients diagnosed with RAS. The patients were instructed to rinse the mouth-wash or placebo three times a day and triamcinolone ointment twice a day for two weeks. The largest dimension of the ulcer was measured by a digital caliper and the severity of pain was assessed by visual analogue scale (VAS). Number, size, dura-tion, ulcer-free period and pain of the lesions were evaluated twice a week for twomonths. Data were analyzed by SPSS 16 using Mann-Whitney U test and t-test. Results. A decrease was seen in the mean pain severity score (P = 0.631) and the size of the lesions but it was not statisti-cally significant (P = 0.739). Also the difference between the number of lesions (P = 0.739), duration and ulcer-free period (P = 0.873) were not statistically significant. Conclusion. Zinc mouthwash seems to be as effective on wound healing process as typical treatment modalities for RAS.

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نویسنده نفر چندم مقاله
معصومه مهدی پوراول
علی تقوی زنوزدوم
آذین سهرابیسوم
نرگس قلیزادهچهارم
آیلا بهرامیانپنجم
زهرا جمالیششم

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