The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells
The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells
نویسندگان: کریم شمس اسنجان , مهشید صالح , علی اکبر موثق پور اکبری , پروین اکبرزاده لاله , زهرا مولائی پور
کلمات کلیدی: Differentiation, Mesenchymal Stem Cells, Hematopoietic Stem Cells
نشریه: 951 , 3 , 5 , 2015
| نویسنده ثبت کننده مقاله |
کریم شمس اسنجان |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات هماتولوژی و انکولوژی |
| کد مقاله |
58771 |
| عنوان فارسی مقاله |
The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells |
| عنوان لاتین مقاله |
The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح دو – PubMed |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
http://www.ncbi.nlm.nih.gov/pubmed/26504750 |
| The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells
Abstract
Bone marrow microenvironment contains cellular and acellular compartments. The cellular
compartment includes hematopoietic stem cells, mesenchymal stem cells and some other
stromal cell types, while the acellular compartment is composed of scaffold proteins known
as the extra cellular matrix. Direct cell-cell contact as well as cytokines secreted by
mesenchymal stem cells during coculture of hematopoietic stem cells and mesenchymal
stem cells play a critical role in hematopoiesis, and determines the fate of hematopoietic
stem cells. Several studies have demonstrated the impact of mesenchymal stem cells on
self-renewal, expansion, proliferation and differentiation of hematopoietic stem cells in
vitro, which have shown different and contradictory results. In this paper, we will
investigate the effect of mesenchymal stem cells on differentiation of hematopoietic stem
cells in vitro |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells.pdf | 1395/06/28 | 483353 | دانلود |