چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | ناصر احمدی اصل |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات کاربردی دارویی |
| کد مقاله | 58764 |
| عنوان فارسی مقاله | Expression of the Mir-133 and Bcl-2 could be affected by swimming training in the heart of ovariectomized rats |
| عنوان لاتین مقاله | Expression of the Mir-133 and Bcl-2 could be affected by swimming training in the heart of ovariectomized rats |
| ناشر | 6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://ijbms.mums.ac.ir/article_6809.html |
| Objective(s): The beneficial and more potent role of exercise to prevent heart apoptosis in ovariectomized rats has been known. The aim of this study was to examine the effects of swimming training on cardiac expression of Bcl‐2, and Mir‐133 levels and glycogen changes in the myocyte. Materials and Methods: Forty animals were separated into four groups as control, sham, ovariectomy (OVX) and ovariectomized group with 8 weeks swimming training (OVX.E). Training effects were evaluated by measuring lipid profiles, Bcl‐2 and Mir‐133 expression levels in the cardiac tissue. Grafts were analyzed by reverse transcription–polymerase chain reaction for Bcl‐2 mRNA and Mir‐ 133 and by Western blot for Bcl‐2 protein. Results: Ovariectomy down‐regulated Bcl‐2 and Mir‐133 expression levels in the cardiac tissue, and swimming training up‐regulated their expression significantly (P<0.05). Conclusion: Our results showed that regular exercise as a physical replacement therapy could prevent and improve the effects of estrogen deficiency in the cardia. |
| نویسنده | نفر چندم مقاله |
|---|---|
| ناصر احمدی اصل | پنجم |
| پریسا حبیبی | اول |
| علیرضا علی همتی | دوم |
| هادی یوسفی | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Expression of the Mir-133 and Bcl-2 could be affected by swimming training in the heart of ovariectomized rats.pdf | 1395/06/27 | 1080174 | دانلود |
