چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | سعید دستگیری |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات مدیریت خدمات بهداشتی درمانی تبریز |
| کد مقاله | 58701 |
| عنوان فارسی مقاله | Blood transfusions for treating acute chest syndrome in people with sickle cell disease |
| عنوان لاتین مقاله | Blood transfusions for treating acute chest syndrome in people with sickle cell disease |
| ناشر | 2 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Review Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007843.pub3/full |
| Background Sickle cell disease is an inherited autosomal recessive blood condition and is one of themost prevalent genetic blood diseases worldwide. Acute chest syndrome is a frequent complication of sickle cell disease, as well as a major cause of morbidity and the greatest single cause of mortality in children with sickle cell disease. Standard treatment may include intravenous hydration, oxygen as treatment for hypoxia, antibiotics to treat the infectious cause and blood transfusions may be given. This is an update of a Cochrane review first published in 2010. Objectives To assess the effectiveness of blood transfusions, simple and exchange, for treating acute chest syndrome by comparing improvement in symptoms and clinical outcomes against standard care. Search methods We searched The Cochrane Cystic Fibrosis and Genetic Disorders Group’s Haemoglobinopathies Trials Register, which comprises references identified from comprehensive electronic database searches and handsearching of relevant journals and abstract books of conference proceedings. Date of the most recent search: 25 April 2016. Selection criteria Randomised controlled trials and quasi-randomised controlled trials comparing either simple or exchange transfusion versus standard care (no transfusion) in people with sickle cell disease suffering from acute chest syndrome. Data collection and analysis Both authors independently selected trials and assessed the risk of bias, no data could be extracted. Main results One trial was eligible for inclusion in the review. While in the multicentre trial 237 people were enrolled (169 SCC, 42 SC, 15 S - thalassemia, 11S +-thalassemia); themajority were recruited to an observational armand only ten participants met the inclusion criteria for randomisation. Of these, four were randomised to the transfusion arm and received a single transfusion of 7 to 13 ml/kg packed red blood cells, and six were randomised to standard care. None of the four participants who received packed red blood cells developed acute chest syndrome, while 33% (two participants) developed acute chest syndrome in standard care arm. No data for any pre-defined outcomes were available. |
| نویسنده | نفر چندم مقاله |
|---|---|
| سعید دستگیری | اول |
| رویا دولت خواه | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Dastgiri_et_al-2016-The_Cochrane_Library (1).pdf | 1395/06/21 | 248457 | دانلود |
