Correlation between major depressive disorder and circulating natural killer cells
Correlation between major depressive disorder and circulating natural killer cells
نویسندگان: علیرضا فرنام , سید غلامرضا نورآذر , علی اکبر موثق پور اکبری
کلمات کلیدی: major depressive disorder, natural killer cells
نشریه: , 2 , 1 , 2015
| نویسنده ثبت کننده مقاله |
علیرضا فرنام |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
روانپزشکی و علوم رفتاری |
| کد مقاله |
58630 |
| عنوان فارسی مقاله |
Correlation between major depressive disorder and circulating natural killer cells |
| عنوان لاتین مقاله |
Correlation between major depressive disorder and circulating natural killer cells |
| ناشر |
7 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
|
| عنوان نشریه (خارج از لیست فوق) |
Archives of Medical Laboratory Sciences |
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس نشده |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
http://journals.sbmu.ac.ir/archives/article/view/10245 |
| Background: Major depressive disorder is a mental disorder characterized by a pervasive and persistent low mood
that is accompanied by low self-esteem and loss of interest or pleasure in normally enjoyable activities. Depression
is associated with multiple immunological disorders. Aim of the present study was to determine correlation between
percentage of circulating NK cells and major depressive disorder. Materials and Methods: Patients older than 18
years with the desire to participate were enrolled in this study. For depression evaluation, we used the Hamilton
Depression Rating Scale and for determination of percentage of NK cells in peripheral blood, flow cytometry
method was used. Results: Our results showed that in patients with major depressive disorder, numbers of
circulating NK cells have significantly reduced. Conclusion: According to our findings, depression is associated
with “immune suppression”. NK cells are important in early phase of immunological surveillance versus viral
infections and tumors. Indeed, depressive patients are susceptible to cancers and infections. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 10245-47989-1-PB.pdf | 1395/06/13 | 470692 | دانلود |