The Association between Anthropometric Indices and Disease Severity in Women with Rheumatoid Arthritis

The Association between Anthropometric Indices and Disease Severity in Women with Rheumatoid Arthritis


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نویسندگان: ندا قمرزاد شیشوان , بهرام پورقاسم گرگری , محمد اصغری جعفرآبادی

کلمات کلیدی: Keywords: Rheumatoid Arthritis, Obesity, Inflammation

نشریه: 36322 , 4 , 37 , 2015

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نویسنده ثبت کننده مقاله سوسن کلاهی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه بیماری های بافت همبند
کد مقاله 58502
عنوان فارسی مقاله The Association between Anthropometric Indices and Disease Severity in Women with Rheumatoid Arthritis
عنوان لاتین مقاله The Association between Anthropometric Indices and Disease Severity in Women with Rheumatoid Arthritis
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق) Medical Journal of Tabriz University of Medical Sciences and Health Services
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح چهار – ISC - Islamic Science Citation
آدرس لینک مقاله/ همایش در شبکه اینترنت Medical Journal of Tabriz University of Medical Sciences and Health Services

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Background & Objectives: Rheumatoid arthritis (RA) is an autoimmune disease that inflammatory mediators has an important role in its pathogenesis and leads to bone and joints destruction. This inflammatory status can be effected by different factors such as genetic, dietary intakes and hormonal factors. However, the influence of anthropometric on the severity of RA and inflammatory markers is still debatable. Material & Methods: The current study was done on a group of patients with documented RA who were under regular visit in our university hospital outpatients clinic from the start until the end of 2012. Based on DAS-28 criteria disease activity was assessed by a rheumatology specialist. Anthropometric measurements included body mass index (BMI), Waist to hip ratio (WHR),Waist to Height Ratio (WHtR) all were measured serum levels of highly sensetive cpp IL-6 and MMP-3, were measured in fasting serum samples. Results: There was a Positive correlation between obesity (body mass index and waist to height ratio) and disease activity score and serum levels of hsCRP (P <0.05). There was no significant correlation between obesity with serum levels of MMP-3 and IL-6 (P > 0.05). Conclusion: Present study indicates a significant direct correlation between obesity and disease activity and systemic inflammation marker (hscRP). In RA thus, control of weight could be a very important strategy for maintenance remission in rheumatoid arthritis.

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نویسنده نفر چندم مقاله
ندا قمرزاد شیشواناول
بهرام پورقاسم گرگریچهارم
محمد اصغری جعفرآبادیششم

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