چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | فائزه قالیچی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات علوم تغذیه |
| کد مقاله | 58478 |
| عنوان فارسی مقاله | تأثیر رژیم غذایی بدون گلوتن بر شاخصهای رفتاری و گوارشی در بیماران مبتلا به اختلالات طیف اوتیسم |
| عنوان لاتین مقاله | Effectiveness of the gluten free diet on gastrointestinal and behavioral indices for children with Autism Spectrum Disorders: A randomized clinical trial |
| ناشر | 4 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | بلی |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://link.springer.com/article/10.1007/s12519-016-0040-z |
| Effectiveness of the gluten free diet on gastrointestinal and behavioral indices for children with Autism Spectrum Disorders: A randomized clinical trial Abstract Background. – Genetic and environmental factors are both responsible in the etiology of Autism Spectrum Disorders (ASD). Although numerous epidemiological studies have been conducted to clarify the association between restriction diets and ASD, the conclusion still remains unclear. The objective of this study is to investigate the effectiveness of the Gluten Free Diet (GFD) on gastrointestinal symptoms and behavioral indices in children with ASD. Methods. – In this randomized clinical trial, 80 individuals diagnosed with ASD by the Autism Diagnostic Interview-Revised (ADI-R) were assigned into the GFD (n=40) and Regular Diet (RD) (n=40) groups for 6 weeks. At the beginning and end of the intervention, the ROME Ш questionnaire for evaluating gastrointestinal symptoms and Gilliam Autism Rating Scale 2 questionnaire (GARS-2) for assessing psychometric properties were completed. Results. – Among 80 children diagnosed with ASD, 53.9% of the total patients had gastrointestinal abnormalities, 55.3% of the individuals belonged to the GFD group and 52.6% were in the RD group. In the GFD group, gastrointestinal symptoms decreased significantly (P<0.05) after implementing the GFD (40.57% vs. 17.10%) while it increased insignificantly in the regular diet (RD) group (42.45% vs. 44.05%). GFD intervention resulted in a significant (P<0.05) decline in behavioral disorders (80.03±14.07 vs. 75.82±15.37) whereas it augmented insignificantly in the RD group (79.92±15.49 vs. 80.92±16.24). Conclusions. – This study provides evidence that the GFD may be an effective treatment for controlling gastrointestinal symptoms and ASD behaviors. Nevertheless, further comprehensive and accurate studies are imperative to clarify the issue. |
| نویسنده | نفر چندم مقاله |
|---|---|
| علیرضا استاد رحیمی | چهارم |
| فائزه قالیچی | اول |
| سید جمال قائم مقامی هزاوه | دوم |
| ایوب مالک | سوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| manuscript.doc | 1395/05/15 | 132608 | دانلود |
| Ghalichi-paper1.pdf | 1395/05/24 | 233903 | دانلود |
